Profen and Ranolazine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Profen (ibuprofen) and Ranolazine (ranolazine). Common drug interactions include carotid artery occlusion among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Profen and Ranolazine. It is created by eHealthMe based on reports of 80 people who take the same drugs from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

What is Ranolazine?

Ranolazine has active ingredients of ranolazine. eHealthMe is studying from 9,939 Ranolazine users. Check the latest studies of Ranolazine.

On Jul, 20, 2026

80 people who take Profen and Ranolazine together, and have interactions are studied.

Profen and Ranolazine drug interactions.

What are the common drug interactions of Profen and Ranolazine, by gender? *:

female:

Carotid artery occlusion (artery blockage)
Carotid artery stenosis (narrowing of carotid artery)
Cerebral atrophy (decrement in size of brain)
Dizziness
Head injury
Idiopathic pulmonary fibrosis (chronic lung disease)
Low density lipoprotein increased (cholesterol increased in blood)
Mitral valve incompetence (inefficient heart valve)
Myocardial ischaemia (the blood flow through one or more of the blood vessels that lead to heart (coronary arteries) is decreased)
Rash

male:

Nausea (feeling of having an urge to vomit)
Chest pain
Fatigue (feeling of tiredness)
Glossitis (infection of tongue with soreness)
Sepsis (a severe blood infection that can lead to organ failure and death)
Anaemia (lack of blood)
Cardiac failure
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Memory impairment
Mucosal inflammation (infection of mucous membrane)

What are the common drug interactions of Profen and Ranolazine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Osteopenia (a condition where bone mineral density is lower than normal)
Osteoporosis (bones weak and more likely to break)
Renal injury (kidney injury)
Spinal compression fracture (fracture due to spinal compression on bone)
Chronic kidney disease
Chest pain
Insomnia (sleeplessness)
Muscle twitching
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Back disorder

50-59:

Age-related macular degeneration
Cystoid macular oedema (fluid accumulation after cataract surgery)
Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest)

60+:

Chest pain
Dyspnoea (difficult or laboured respiration)
Haematochezia (passage of stools containing blood)
Pyrexia (fever)
Fall
Glossitis (infection of tongue with soreness)
Sepsis (a severe blood infection that can lead to organ failure and death)
Fatigue (feeling of tiredness)
Dizziness
Anaemia (lack of blood)

What are the existing conditions these people have? *

High Blood Pressure: 27 people, 33.75%
High Blood Cholesterol: 25 people, 31.25%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 19 people, 23.75%
Chest Pain: 18 people, 22.50%
Stress And Anxiety: 17 people, 21.25%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 13 people, 16.25%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 11 people, 13.75%
Type 2 Diabetes: 11 people, 13.75%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 11 people, 13.75%
Oedema (fluid collection in tissue): 10 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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