Profen and Uceris drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Profen (ibuprofen) and Uceris (budesonide). Common drug interactions include crohn's disease among females and emotional distress among males.
The phase IV clinical study analyzes what interactions people have when they take Profen and Uceris. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.
What is Profen?
Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.
What is Uceris?
Uceris has active ingredients of budesonide. It is often used in ulcerative colitis. eHealthMe is studying from 1,721 Uceris users. Check the latest studies of Uceris.
18 people who take Profen and Uceris together, and have interactions are studied.

What are the common drug interactions of Profen and Uceris, by gender? *:
female:
- Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
- Ankle fracture
- Diarrhoea
- Faeces discoloured
- Rhinorrhoea (watery mucus discharge from the nose)
- Abdominal pain
- Alanine aminotransferase increased
- Alopecia (absence of hair from areas of the body)
- Aspartate aminotransferase increased
- Asthma
male:
- Emotional distress
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Muscle atrophy (a decrease in the mass of the muscle)
- Quality of life decreased
- Rib fracture
- Depression
- Renal failure (kidney dysfunction)
- Abdominal discomfort
- Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
- Dehydration (dryness resulting from the removal of water)
What are the common drug interactions of Profen and Uceris, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Beta haemolytic streptococcal infection (infection with streptococcus pyogenes, a beta-haemolytic bacterium cause mild to moderately severe respiratory tract, skin, and soft tissue)
- Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
- Dehydration (dryness resulting from the removal of water)
- Depression
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Migraine (headache)
- Raynaud's phenomenon (discoloration of the fingers, toes, and occasionally other areas)
- Sinusitis (inflammation of sinus)
30-39:
n/a
40-49:
n/a
50-59:
- Emotional distress
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Osteopenia (a condition where bone mineral density is lower than normal)
- Blood calcium decreased
- Decreased activity
- Foot fracture
- Grip strength decreased
- Hand fracture
- Multiple fractures
60+:
- Diarrhoea
- Faeces discoloured
- Abdominal discomfort
- Alanine aminotransferase increased
- Alopecia (absence of hair from areas of the body)
- Aspartate aminotransferase increased
- Drug ineffective
- Haematochezia (passage of stools containing blood)
- Hypertension (high blood pressure)
- Sleep disorder
What are the existing conditions these people have? *
- High Blood Pressure: 6 people, 33.33%
- Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 6 people, 33.33%
- Diarrhea: 6 people, 33.33%
- Viral Infection: 5 people, 27.78%
- Asthma: 5 people, 27.78%
- Bacterial Infection: 5 people, 27.78%
- Depression: 5 people, 27.78%
- Fungal Infection: 5 people, 27.78%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 27.78%
- High Blood Cholesterol: 5 people, 27.78%
* Approximation only. Some reports may have incomplete information.
Do you take Profen and Uceris?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Profen and Uceris:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Profen:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Uceris:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Profen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Uceris and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
How the study uses the data?
The study uses data from the FDA. It is based on ibuprofen and budesonide (the active ingredients of Profen and Uceris, respectively), and Profen and Uceris (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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