Profen and Valine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Profen (ibuprofen) and Valine (branched - chain amino acids). Common drug interactions include alopecia among females.

The phase IV clinical study analyzes what interactions people have when they take Profen and Valine. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Profen?

Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.

What is Valine?

Valine has active ingredients of branched - chain amino acids. eHealthMe is studying from 367 Valine users. Check the latest studies of Valine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 25, 2026

13 people who take Profen and Valine together, and have interactions are studied.

What are the common drug interactions of Profen and Valine, by gender? *:

female:

Alopecia (absence of hair from areas of the body)
Hypersensitivity
Stomatitis (inflammation of mucous membrane of mouth)
Abdominal pain upper
Asthenia (weakness)
Blood cholesterol increased
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Confusional state
Dizziness
Dry mouth

male:

n/a

What are the common drug interactions of Profen and Valine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Alopecia (absence of hair from areas of the body)
Hypersensitivity
Stomatitis (inflammation of mucous membrane of mouth)
Abdominal pain upper
Asthenia (weakness)
Blood cholesterol increased
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Confusional state
Dizziness
Dry mouth

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 13 people, 100.00%
Stress And Anxiety: 4 people, 30.77%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 3 people, 23.08%
Psoriasis (immune-mediated disease that affects the skin): 3 people, 23.08%
Indigestion: 2 people, 15.38%
Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 15.38%
Migraine (headache): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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