Profen and Zemuron drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Profen (ibuprofen) and Zemuron (rocuronium bromide). Common drug interactions include necrotising fasciitis among females and cellulitis among males.
The phase IV clinical study analyzes what interactions people have when they take Profen and Zemuron. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.
What is Profen?
Profen has active ingredients of ibuprofen. It is often used in pain. eHealthMe is studying from 245,311 Profen users. Check the latest studies of Profen.
What is Zemuron?
Zemuron has active ingredients of rocuronium bromide. eHealthMe is studying from 873 Zemuron users. Check the latest studies of Zemuron.
28 people who take Profen and Zemuron together, and have interactions are studied.

What are the common drug interactions of Profen and Zemuron, by gender? *:
female:
- Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
- Perirectal abscess
- Renal failure (kidney dysfunction)
- Abscess limb (limb infection)
- Anal abscess
- Cellulitis (infection under the skin)
- Chronic kidney disease
- Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Genital abscess (build up of pus in genital)
male:
- Cellulitis (infection under the skin)
- Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Coronary artery stenosis (narrowing of coronary artery)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Dizziness
- Dyslipidaemia (abnormal amount of lipids)
- Eructation (release of gas from the digestive tract)
- Exposed bone in jaw
- Genital abscess (build up of pus in genital)
What are the common drug interactions of Profen and Zemuron, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Pulmonary embolism (blockage of the main artery of the lung)
30-39:
n/a
40-49:
- Testicular abscess (pus in testes)
- Testicular pain (pain in testes)
- Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
- Anal abscess
- Genital abscess (build up of pus in genital)
- Tooth abscess (pus formation in tooth)
- Cellulitis (infection under the skin)
- Chronic kidney disease
- Emotional distress
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
50-59:
- Cellulitis (infection under the skin)
- Scrotal swelling
- Cellulitis of male external genital organ (infection of male genitals soft tissue)
- Genital abscess (build up of pus in genital)
- Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
- Scrotal abscess (pus in scrotum)
- Abscess limb (limb infection)
- Anal abscess
- Death
- Depression
60+:
- Abdominal pain
- Anaemia (lack of blood)
- Dyslipidaemia (abnormal amount of lipids)
- Eructation (release of gas from the digestive tract)
- Exposed bone in jaw
- Hunger
- Metastases to bone (cancer spreads to bone)
- Mitral valve incompetence (inefficient heart valve)
- Mouth ulceration (mouth ulcers)
- Nausea (feeling of having an urge to vomit)
What are the existing conditions these people have? *
- Weight Decreased: 12 people, 42.86%
- Type 2 Diabetes: 12 people, 42.86%
- Hypotension (abnormally low blood pressure): 10 people, 35.71%
- High Blood Pressure: 8 people, 28.57%
- Hypersensitivity: 5 people, 17.86%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 17.86%
- Diabetes: 4 people, 14.29%
- Cardiac Disorder: 4 people, 14.29%
- Blood Pressure Abnormal: 4 people, 14.29%
- Stress And Anxiety: 3 people, 10.71%
* Approximation only. Some reports may have incomplete information.
Do you take Profen and Zemuron?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Profen and Zemuron:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Profen:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Zemuron:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Profen and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zemuron and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
- Moslim MA, Sodeman TC, Nawras AT, "A Case of Suggested Ibuprofen-Induced Acute Pancreatitis", American journal of therapeutics, 2016 Nov .
How the study uses the data?
The study uses data from the FDA. It is based on ibuprofen and rocuronium bromide (the active ingredients of Profen and Zemuron, respectively), and Profen and Zemuron (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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