Progesterone and Meridia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Progesterone (progesterone) and Meridia (sibutramine hydrochloride). Common drug interactions include insomnia among females.

The phase IV clinical study analyzes what interactions people have when they take Progesterone and Meridia. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Progesterone?

Progesterone has active ingredients of progesterone. It is often used in menopause. eHealthMe is studying from 21,021 Progesterone users. Check the latest studies of Progesterone.

What is Meridia?

Meridia has active ingredients of sibutramine hydrochloride. It is often used in weight loss. eHealthMe is studying from 6,939 Meridia users. Check the latest studies of Meridia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 29, 2026

28 people who take Progesterone and Meridia together, and have interactions are studied.

Progesterone and Meridia drug interactions.

What are the common drug interactions of Progesterone and Meridia, by gender? *:

female:

Insomnia (sleeplessness)
Constipation
Nervousness
Palpitations (feelings or sensations that your heart is pounding or racing)
Abnormal dreams
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Appetite increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires)
Asthenia (weakness)
Back pain
Chest pain

male:

n/a

What are the common drug interactions of Progesterone and Meridia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Appetite increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires)
Constipation
Dry mouth

40-49:

Insomnia (sleeplessness)
Abdominal distension
Abnormal dreams
Anxiety
Back pain
Constipation
Disturbance in attention
Dry mouth
Feeling jittery
Heart rate increased

50-59:

Nausea (feeling of having an urge to vomit)
Abdominal distension
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Anxiety
Asthenia (weakness)
Chest pain
Chronic kidney disease
Constipation
Diarrhoea
Facial palsy (paralysis of face nerve)

60+:

Death sudden
Drug ineffective
Dyspnoea (difficult or laboured respiration)
Palpitations (feelings or sensations that your heart is pounding or racing)
Pulmonary embolism (blockage of the main artery of the lung)
Unexpected therapeutic effect

What are the existing conditions these people have? *

Weight Loss: 2 people, 7.14%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 7.14%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 2 people, 7.14%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 2 people, 7.14%
Cardiac Failure Congestive: 2 people, 7.14%
Constipation: 2 people, 7.14%
Depression: 2 people, 7.14%
Diabetes: 2 people, 7.14%
Diarrhea: 2 people, 7.14%
Eye Infection: 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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