Prograf and Nizoral drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prograf (tacrolimus) and Nizoral (ketoconazole). Common drug interactions include abdominal pain among females and colitis ulcerative among males.

The phase IV clinical study analyzes what interactions people have when they take Prograf and Nizoral. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Prograf?

Prograf has active ingredients of tacrolimus. It is often used in kidney transplant. eHealthMe is studying from 42,230 Prograf users. Check the latest studies of Prograf.

What is Nizoral?

Nizoral has active ingredients of ketoconazole. It is often used in seborrheic dermatitis. eHealthMe is studying from 5,836 Nizoral users. Check the latest studies of Nizoral.



On Jul, 13, 2026

22 people who take Prograf and Nizoral together, and have interactions are studied.

Prograf and Nizoral drug interactions.

What are the common drug interactions of Prograf and Nizoral, by gender? *:

female:

  1. Abdominal pain
  2. Headache (pain in head)
  3. Influenza
  4. Nausea (feeling of having an urge to vomit)
  5. Rash pruritic (redness with itching)
  6. Anaemia (lack of blood)
  7. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  8. Blood creatinine increased
  9. Confusional state
  10. Deafness

male:

  1. Colitis ulcerative (inflammation of colon with ulcer)
  2. Herpes zoster
  3. Drug ineffective
  4. Fatigue (feeling of tiredness)
  5. Humerus fracture (injury to the upper arm bone)
  6. Hyperglycaemia (high blood sugar)
  7. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  8. Sepsis (a severe blood infection that can lead to organ failure and death)
  9. Anaemia (lack of blood)
  10. Anxiety

What are the common drug interactions of Prograf and Nizoral, by age (0-1 to 60+)? *:

0-1:

  1. Hydrocele
  2. Maternal exposure before pregnancy (use of substance before pregnancy)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Anaemia (lack of blood)
  2. Abdominal pain
  3. Headache (pain in head)
  4. Influenza
  5. Nausea (feeling of having an urge to vomit)
  6. Rash pruritic (redness with itching)
  7. Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
  8. Eye haemorrhage (bleeding in the eye)
  9. Fungal skin infection
  10. Herpes zoster

40-49:

  1. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  2. Chronic kidney disease
  3. Depression
  4. Nephrogenic anaemia (anaemia due to kidney disease)
  5. Renal failure (kidney dysfunction)
  6. Renal injury (kidney injury)

50-59:

  1. Drug ineffective
  2. International normalised ratio decreased
  3. Vascular graft complication

60+:

  1. Colitis ulcerative (inflammation of colon with ulcer)
  2. Herpes zoster
  3. Humerus fracture (injury to the upper arm bone)
  4. Hyperglycaemia (high blood sugar)
  5. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  6. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  7. Blood creatinine increased
  8. Confusional state
  9. Deafness
  10. Death

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 22.73%
  2. High Blood Pressure: 4 people, 18.18%
  3. Parkinson's Disease: 3 people, 13.64%
  4. Conjunctivitis Allergic (inflammation of the conjunctiva due to allergy): 3 people, 13.64%
  5. Athlete's Foot (a fungal infection affecting the skin between the toes): 3 people, 13.64%
  6. Asteatosis (any disease that persistently causes the skin to dry): 3 people, 13.64%
  7. Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 2 people, 9.09%
  8. Pain: 2 people, 9.09%
  9. Nasopharyngitis (inflammation of the nasopharynx): 2 people, 9.09%
  10. Itching: 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Prograf and Nizoral?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Prograf and Nizoral:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prograf:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Nizoral:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prograf and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nizoral and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on tacrolimus and ketoconazole (the active ingredients of Prograf and Nizoral, respectively), and Prograf and Nizoral (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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