Promethazine and Bicalutamide drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Promethazine (promethazine hydrochloride) and Bicalutamide (bicalutamide). Common drug interactions include chest pain among females and dermatitis among males.

The phase IV clinical study analyzes what interactions people have when they take Promethazine and Bicalutamide. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Promethazine?

Promethazine has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 32,300 Promethazine users. Check the latest studies of Promethazine.

What is Bicalutamide?

Bicalutamide has active ingredients of bicalutamide. It is often used in prostate cancer. eHealthMe is studying from 9,930 Bicalutamide users. Check the latest studies of Bicalutamide.

On Jul, 10, 2026

45 people who take Promethazine and Bicalutamide together, and have interactions are studied.

Promethazine and Bicalutamide drug interactions.

What are the common drug interactions of Promethazine and Bicalutamide, by gender? *:

female:

Chest pain
Chills (felling of cold)
Costochondritis (chest wall pain)
Decreased interest
Dental caries
Depression
Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Dizziness
Dysuria (painful or difficult urination)
Electrocardiogram qt prolonged

male:

Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Fatigue (feeling of tiredness)
Depressed mood
Dyspnoea exertional (breathlessness or shortness of breath)
Fluid retention (an abnormal accumulation of fluid in the blood)
General physical health deterioration (weak health status)
Haemoglobin decreased
International normalised ratio increased
Lethargy (tiredness)
Memory impairment

What are the common drug interactions of Promethazine and Bicalutamide, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abscess limb (limb infection)
Cellulitis of male external genital organ (infection of male genitals soft tissue)
Chronic kidney disease
Hyperkalaemia (damage to or disease of the kidney)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Nephrogenic anaemia (anaemia due to kidney disease)
Orchitis (inflammation of the testes)
Scrotal abscess (pus in scrotum)
Sepsis (a severe blood infection that can lead to organ failure and death)
Urinary tract infection

30-39:

n/a

40-49:

Gingival pain (gum pain)
Gingival swelling (gums swelling)
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Gynaecomastia (enlargement of the gland tissue of the male breast)
Haematocrit decreased
Haemoglobin decreased
Hot flush (sudden feelings of heat)
Hyperlipidaemia (presence of excess lipids in the blood)
Hypoaesthesia (reduced sense of touch or sensation)
Impaired healing

50-59:

Gout (uric acid crystals building up in the body)
Death

60+:

Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Fatigue (feeling of tiredness)
Dyspnoea exertional (breathlessness or shortness of breath)
Fluid retention (an abnormal accumulation of fluid in the blood)
General physical health deterioration (weak health status)
Haemoglobin decreased
International normalised ratio increased
Lethargy (tiredness)
Memory impairment
Oedema peripheral (superficial swelling)

What are the existing conditions these people have? *

Prostate Cancer Metastatic: 4 people, 8.89%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 6.67%
Pain: 3 people, 6.67%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 3 people, 6.67%
Insomnia (sleeplessness): 3 people, 6.67%
Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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