Promethazine and Ceftazidime drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Promethazine (promethazine hydrochloride) and Ceftazidime (ceftazidime). Common drug interactions include essential hypertension among females and white blood cell count decreased among males.
The phase IV clinical study analyzes what interactions people have when they take Promethazine and Ceftazidime. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.
What is Promethazine?
Promethazine has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 32,300 Promethazine users. Check the latest studies of Promethazine.
What is Ceftazidime?
Ceftazidime has active ingredients of ceftazidime. eHealthMe is studying from 10,327 Ceftazidime users. Check the latest studies of Ceftazidime.
42 people who take Promethazine and Ceftazidime together, and have interactions are studied.

What are the common drug interactions of Promethazine and Ceftazidime, by gender? *:
female:
- Essential hypertension (primary hypertension)
- Gastrointestinal infection (infection of stomach and intestine)
- Headache (pain in head)
- Mitral valve incompetence (inefficient heart valve)
- Pharyngeal haemorrhage (pharyngeal bleeding)
- Rash
- Renal failure (kidney dysfunction)
- Renal impairment (severely reduced kidney function)
- Sinusitis (inflammation of sinus)
- Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
male:
- White blood cell count decreased
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
- Anxiety
- Dehydration (dryness resulting from the removal of water)
- Depression
- Pain
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Abdominal distension
What are the common drug interactions of Promethazine and Ceftazidime, by age (0-1 to 60+)? *:
0-1:
- Hypernatraemia (an abnormally high plasma concentration of sodium ions)
- Haematocrit increased
- Pulseless electrical activity
- Septic shock (shock due to blood infection)
- Systemic inflammatory response syndrome (an inflammatory state affecting the whole body, frequently a response of the immune system to infection)
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Emotional distress
- Pain
- Urinary tract infection
- Death
- Renal impairment (severely reduced kidney function)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
50-59:
- Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
- Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
60+:
- White blood cell count decreased
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
- Anaemia (lack of blood)
- Platelet count decreased
- Cardiac failure
- Intestinal obstruction
- Thrombocytopenia (decrease of platelets in blood)
- Constipation
What are the existing conditions these people have? *
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 9 people, 21.43%
- Pain: 8 people, 19.05%
- Insomnia (sleeplessness): 7 people, 16.67%
- Pneumonia: 7 people, 16.67%
- Fever: 6 people, 14.29%
- Hypokalemia (low potassium): 5 people, 11.90%
- Infection: 5 people, 11.90%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 5 people, 11.90%
- Multiple Myeloma (cancer of the plasma cells): 5 people, 11.90%
- Fungal Infection: 5 people, 11.90%
* Approximation only. Some reports may have incomplete information.
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Promethazine (32,300 reports)
- Ceftazidime (10,327 reports)
Browse all drug interactions of Promethazine and Ceftazidime:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Promethazine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ceftazidime:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Promethazine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ceftazidime and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Chen F, Zhan Z, "Severe drug-induced immune haemolytic anaemia due to ceftazidime", Blood Transfusion, 2014 Jan .
- Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
- Chen F, Zhan Z, "Severe drug-induced immune haemolytic anaemia due to ceftazidime", Blood Transfusion, 2014 Jan .
- Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on promethazine hydrochloride and ceftazidime (the active ingredients of Promethazine and Ceftazidime, respectively), and Promethazine and Ceftazidime (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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