Promethazine and Neupogen drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Promethazine (promethazine hydrochloride) and Neupogen (filgrastim). Common drug interactions include febrile neutropenia among females and dermatitis among males.

The phase IV clinical study analyzes what interactions people have when they take Promethazine and Neupogen. It is created by eHealthMe based on reports of 84 people who take the same drugs from the FDA, and is updated regularly.

What is Promethazine?

Promethazine has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 32,300 Promethazine users. Check the latest studies of Promethazine.

What is Neupogen?

Neupogen has active ingredients of filgrastim. It is often used in agranulocytosis. eHealthMe is studying from 23,898 Neupogen users. Check the latest studies of Neupogen.

On Aug, 09, 2026

84 people who take Promethazine and Neupogen together, and have interactions are studied.

Promethazine and Neupogen drug interactions.

What are the common drug interactions of Promethazine and Neupogen, by gender? *:

female:

Febrile neutropenia (fever with reduced white blood cells)
Alopecia (absence of hair from areas of the body)
Anaemia (lack of blood)
Urinary tract infection
White blood cell count decreased
Abdominal pain upper
Colitis (inflammation of colon)
Cough
Respiratory tract infection
Decreased appetite

male:

Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Diarrhoea
Facial nerve disorder (disease of face nerve)
Hyperhidrosis (abnormally increased sweating)
Cardiac failure congestive
Pyrexia (fever)
Adverse event
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Benign prostatic hyperplasia (benign enlargement of the prostate)

What are the common drug interactions of Promethazine and Neupogen, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Febrile neutropenia (fever with reduced white blood cells)
Drug diversion

30-39:

Hepatic enzyme increased
Sepsis (a severe blood infection that can lead to organ failure and death)
Drug hypersensitivity
Lip swelling
Paraesthesia oral (sensation of tingling, tickling, prickling, pricking, or burning of a person's oral with no apparent long-term physical effect)
Skin reaction
Swollen tongue (swelling of tongue)
Throat tightness
Disease progression
Hepatic steatosis (fatty liver disease)

40-49:

Anaemia (lack of blood)
Ascites (accumulation of fluid in the abdominal cavity)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Febrile neutropenia (fever with reduced white blood cells)
International normalised ratio increased

50-59:

Large intestine perforation (hole in large intestine)
Constipation
Dehydration (dryness resulting from the removal of water)
Depression
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
White blood cell count decreased
Abdominal discomfort
Asthenia (weakness)
Back pain

60+:

Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Abdominal pain upper
Herpes zoster
Respiratory tract infection
Dyspnoea (difficult or laboured respiration)
Facial nerve disorder (disease of face nerve)
Hyperhidrosis (abnormally increased sweating)
Cough
Diarrhoea

What are the existing conditions these people have? *

Pain: 15 people, 17.86%
Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 15 people, 17.86%
Multiple Myeloma (cancer of the plasma cells): 14 people, 16.67%
Stress And Anxiety: 14 people, 16.67%
Nausea And Vomiting: 11 people, 13.10%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 10 people, 11.90%
Hyperlipidaemia (presence of excess lipids in the blood): 8 people, 9.52%
Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 8 people, 9.52%
Osteoporosis (bones weak and more likely to break): 7 people, 8.33%
High Blood Pressure: 7 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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