Promethazine and Tasigna drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Promethazine (promethazine hydrochloride) and Tasigna (nilotinib hydrochloride monohydrate). Common drug interactions include abdominal tenderness among females and alanine aminotransferase increased among males.

The phase IV clinical study analyzes what interactions people have when they take Promethazine and Tasigna. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Promethazine?

Promethazine has active ingredients of promethazine hydrochloride. It is often used in nausea. eHealthMe is studying from 32,300 Promethazine users. Check the latest studies of Promethazine.

What is Tasigna?

Tasigna has active ingredients of nilotinib hydrochloride monohydrate. It is often used in chronic myelogenous leukemia (cml). eHealthMe is studying from 31,535 Tasigna users. Check the latest studies of Tasigna.

On Jul, 12, 2026

39 people who take Promethazine and Tasigna together, and have interactions are studied.

Promethazine and Tasigna drug interactions.

What are the common drug interactions of Promethazine and Tasigna, by gender? *:

female:

Abdominal tenderness
Abnormal loss of weight
Anxiety
Aspartate aminotransferase increased
Blood albumin decreased
Blood albumin increased
Blood alkaline phosphatase increased
Blood creatinine decreased
Blood iron decreased
Dizziness

male:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood pressure increased
Heart rate increased
Hypersensitivity
Hypertension (high blood pressure)
Infusion site erythema (reddening of the skin at infusion site)
Infusion site extravasation (flow of (blood or lymph) from infusion site)
Infusion site pruritus (severe itching at infusion site)
Infusion site swelling

What are the common drug interactions of Promethazine and Tasigna, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Diarrhoea
Duodenal ulcer haemorrhage (bleeding duodenal ulcer)
Duodenal ulcer perforation (untreated ulcer can burn through the wall of the stomach)
Dysphagia (a condition in which swallowing is difficult or painful)
Neoplasm malignant (cancer tumour)
Oesophageal adenocarcinoma (a cancer tumour of an epithelium in oesophagus)
Pain
Second primary malignancy (after getting cure a cancer, a new cancer development)
Thyroid neoplasm (tumour of thyroid)
Ventricular extrasystoles (premature cardiac contraction)

40-49:

Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Menstrual disorder (disease of menstrual cycle)
Oedema (fluid collection in tissue)
Abdominal distension
Anxiety
Arthralgia (joint pain)
Asthma
Bone pain

50-59:

Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Blood cholesterol increased
Blood potassium decreased
Breakthrough pain
Chest pain
Constipation
Intervertebral disc degeneration (spinal disc degeneration)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Neck pain
Pain

60+:

Pruritus (severe itching of the skin)
Dizziness
Haemorrhage (bleeding)
Headache (pain in head)
Herpes zoster
Hypertriglyceridaemia (excess of triglycerides in the blood)
Hypopnoea (decrease in the breathing rate)
Malaise (a feeling of general discomfort or uneasiness)
Palpitations (feelings or sensations that your heart is pounding or racing)
Rhinorrhoea (watery mucus discharge from the nose)

What are the existing conditions these people have? *

Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 25 people, 64.10%
Leukaemia (blood or bone marrow cancer): 3 people, 7.69%
Pain: 2 people, 5.13%
Gastrointestinal Stromal Tumor: 2 people, 5.13%

* Approximation only. Some reports may have incomplete information.

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