Propofol and Enflurane drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Propofol (propofol) and Enflurane (enflurane). Common drug interactions include sensation of heaviness among females and cardiac arrest among males.

The phase IV clinical study analyzes what interactions people have when they take Propofol and Enflurane. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Propofol?

Propofol has active ingredients of propofol. It is often used in colonoscopy abnormal. eHealthMe is studying from 38,224 Propofol users. Check the latest studies of Propofol.

What is Enflurane?

Enflurane has active ingredients of enflurane. eHealthMe is studying from 150 Enflurane users. Check the latest studies of Enflurane.

On Jul, 20, 2026

50 people who take Propofol and Enflurane together, and have interactions are studied.

Propofol and Enflurane drug interactions.

What are the common drug interactions of Propofol and Enflurane, by gender? *:

female:

Sensation of heaviness
Speech disorder
Swollen tongue (swelling of tongue)
Tinnitus (a ringing in the ears)
Ventricular fibrillation (abnormally irregular heart rhythm)
Vertigo
Vomiting
Withdrawal syndrome (a discontinuation syndrome is a set of symptoms occurred due to discontinuation of substance)
Alkalosis
Oculogyric crisis (a spasmodic movement of the eyeballs into a fixed position due to medicine reaction)

male:

Cardiac arrest
Hyperaesthesia
Muscle twitching
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Post procedural complication
Postictal state
Tremor (trembling or shaking movements in one or more parts of your body)
Vision blurred
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Anaesthetic complication neurological

What are the common drug interactions of Propofol and Enflurane, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)

10-19:

Angioneurotic oedema (swelling that occurs just beneath the surface of the skin or mucous membranes)
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Tongue oedema (swelling of tongue)
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
Drug hypersensitivity
Enzyme abnormality

20-29:

Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Oxygen saturation decreased
Periorbital oedema (swelling around the eyes)
Hypoxia (low oxygen in tissues)
Oedema (fluid collection in tissue)
Opisthotonus (a condition in which the body is held in an abnormal position)

30-39:

Sensation of heaviness
Tremor (trembling or shaking movements in one or more parts of your body)
Vision blurred
Cardiac arrest
Nausea (feeling of having an urge to vomit)
Weakness
Akinesia (loss of control of voluntary muscle movements)
Anaesthetic complication
Anaesthetic complication neurological
Aura

40-49:

Alkalosis
Oculogyric crisis (a spasmodic movement of the eyeballs into a fixed position due to medicine reaction)
Agitation (state of anxiety or nervous excitement)
Blood creatine phosphokinase increased
Mydriasis (a dilation of the pupil)
Pyrexia (fever)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Confusional state
Delirium (wild excitement)
Dyskinesia (abnormality or impairment of voluntary movement)

50-59:

Apnoea (suspension of external breathing)
Blood cholinesterase decreased
Cardiac arrest
Coma (state of unconsciousness lasting more than six hours)
Hyperaesthesia
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Deafness
Depressed level of consciousness
Hallucination, auditory (perceiving sounds without auditory stimulus)

60+:

Angioedema (rapid swelling of the dermis)
Anaphylactic reaction (serious allergic reaction)
Ventricular fibrillation (abnormally irregular heart rhythm)
Anaphylactoid reaction (type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation)
Cardiac arrest
Coma (state of unconsciousness lasting more than six hours)
Dyspnoea (difficult or laboured respiration)
Glossodynia (a burning or painful sensation in the tongue)
Hypersensitivity
Hypoxic encephalopathy (a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total)

What are the existing conditions these people have? *

Depression: 9 people, 18.00%
Anaesthesia: 9 people, 18.00%

* Approximation only. Some reports may have incomplete information.

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