Propulsid and Theophyl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Propulsid (cisapride monohydrate) and Theophyl (theophylline). Common drug interactions include dry mouth among females and bradycardia among males.

The phase IV clinical study analyzes what interactions people have when they take Propulsid and Theophyl. It is created by eHealthMe based on reports of 43 people who take the same drugs from the FDA, and is updated regularly.

What is Propulsid?

Propulsid has active ingredients of cisapride monohydrate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 8,130 Propulsid users. Check the latest studies of Propulsid.

What is Theophyl?

Theophyl has active ingredients of theophylline. eHealthMe is studying from 19,174 Theophyl users. Check the latest studies of Theophyl.



On Aug, 08, 2026

43 people who take Propulsid and Theophyl together, and have interactions are studied.

Propulsid and Theophyl drug interactions.

What are the common drug interactions of Propulsid and Theophyl, by gender? *:

female:

  1. Dry mouth
  2. Duodenitis (inflammation of the duodenum)
  3. Dysarthria (speech disorder)
  4. Dyspepsia (indigestion)
  5. Dysphagia (a condition in which swallowing is difficult or painful)
  6. Dystonia (abnormal muscle tone)
  7. Early satiety (feeling full before completing a normal sized meal)
  8. Electrocardiogram abnormal
  9. Electrocardiogram qt prolonged
  10. Epistaxis (bleed from the nose)

male:

  1. Bradycardia (abnormally slow heart action)
  2. Cardiac arrest
  3. Atrial tachycardia (rhythm disturbance that arises in the atria)
  4. Back pain
  5. Cardiac failure congestive
  6. Chronic obstructive airways disease
  7. Diarrhoea
  8. Drug maladministration
  9. Dyspepsia (indigestion)
  10. Eructation (release of gas from the digestive tract)

What are the common drug interactions of Propulsid and Theophyl, by age (0-1 to 60+)? *:

0-1:

  1. Aggression
  2. Asthma
  3. Bronchiolitis (inflammation of the membranes lining the bronchioles in lungs)
  4. Epistaxis (bleed from the nose)
  5. Feeding disorder (when children refuse to eat certain food groups)
  6. Heat intolerance (feeling of being overheated)
  7. Vomiting

2-9:

n/a

10-19:

  1. Abnormal behaviour
  2. Aggression
  3. Back pain
  4. Irritability
  5. Personality change

20-29:

n/a

30-39:

  1. Asthma

40-49:

  1. Bradycardia (abnormally slow heart action)
  2. Cardiac arrest
  3. Anxiety
  4. Arrhythmia (irregular heartbeat)
  5. Asthma
  6. Cardiac failure congestive

50-59:

  1. Headache (pain in head)
  2. Dyspnoea (difficult or laboured respiration)
  3. Asthma
  4. Blood cholesterol increased
  5. Chest pain
  6. Depression
  7. Diabetes mellitus non insulin-dependent
  8. Electrocardiogram abnormal
  9. Hypertension (high blood pressure)
  10. Nausea (feeling of having an urge to vomit)

60+:

  1. Dyspnoea (difficult or laboured respiration)
  2. Chronic obstructive airways disease
  3. Bundle branch block left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle)
  4. Cardiac disorder
  5. Cellulitis (infection under the skin)
  6. Chest pain
  7. Confusion
  8. Coronary artery occlusion (complete obstruction of blood flow in a coronary artery)
  9. Dehydration (dryness resulting from the removal of water)
  10. Dyspnoea exertional (breathlessness or shortness of breath)

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Propulsid and Theophyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Propulsid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Theophyl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Propulsid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Theophyl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on cisapride monohydrate and theophylline (the active ingredients of Propulsid and Theophyl, respectively), and Propulsid and Theophyl (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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