Protonix and Takhzyro drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Protonix (pantoprazole sodium) and Takhzyro (lanadelumab-flyo). Common drug interactions include hereditary angioedema among females.

The phase IV clinical study analyzes what interactions people have when they take Protonix and Takhzyro. It is created by eHealthMe based on reports of 50 people who take the same drugs from the FDA, and is updated regularly.

What is Protonix?

Protonix has active ingredients of pantoprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 132,658 Protonix users. Check the latest studies of Protonix.

What is Takhzyro?

Takhzyro has active ingredients of lanadelumab-flyo. eHealthMe is studying from 2,828 Takhzyro users. Check the latest studies of Takhzyro.



On Jul, 15, 2026

50 people who take Protonix and Takhzyro together, and have interactions are studied.

Protonix and Takhzyro drug interactions.

What are the common drug interactions of Protonix and Takhzyro, by gender? *:

female:

  1. Hereditary angioedema (recurrent episodes of severe swelling)
  2. Syncope (loss of consciousness with an inability to maintain postural tone)
  3. Mycotic allergy (fungal allergy)
  4. Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
  5. Headache (pain in head)
  6. Drug hypersensitivity
  7. Urinary tract infection fungal
  8. Injection site swelling
  9. Injection site bruising
  10. Injection site pruritus (severe itching at injection site)

male:

n/a

What are the common drug interactions of Protonix and Takhzyro, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Adverse drug reaction
  2. Hereditary angioedema (recurrent episodes of severe swelling)
  3. Muscle rupture (tear in muscle)
  4. Neoplasm malignant (cancer tumour)
  5. Pain
  6. Rash
  7. Hypertension (high blood pressure)
  8. Pulmonary embolism (blockage of the main artery of the lung)
  9. Type 2 diabetes mellitus

60+:

  1. Syncope (loss of consciousness with an inability to maintain postural tone)
  2. Dehydration (dryness resulting from the removal of water)
  3. Mycotic allergy (fungal allergy)
  4. Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve)
  5. Headache (pain in head)
  6. Drug hypersensitivity
  7. Urinary tract infection fungal
  8. Injection site swelling
  9. Injection site bruising
  10. Injection site pruritus (severe itching at injection site)

What are the existing conditions these people have? *

  1. Hereditary Angioedema (recurrent episodes of severe swelling): 32 people, 64.00%
  2. Immune System Disorder: 12 people, 24.00%
  3. Osteoporosis (bones weak and more likely to break): 5 people, 10.00%
  4. Immunodeficiency Common Variable: 5 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Protonix and Takhzyro?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Protonix and Takhzyro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Protonix:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Takhzyro:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Protonix and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Takhzyro and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on pantoprazole sodium and lanadelumab-flyo (the active ingredients of Protonix and Takhzyro, respectively), and Protonix and Takhzyro (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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