Protopic and Levaquin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Protopic (tacrolimus) and Levaquin (levofloxacin). Common drug interactions include deafness among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Protopic and Levaquin. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Protopic?

Protopic has active ingredients of tacrolimus. It is often used in eczema. eHealthMe is studying from 5,403 Protopic users. Check the latest studies of Protopic.

What is Levaquin?

Levaquin has active ingredients of levofloxacin. It is often used in sinusitis. eHealthMe is studying from 56,638 Levaquin users. Check the latest studies of Levaquin.

On Jul, 19, 2026

45 people who take Protopic and Levaquin together, and have interactions are studied.

Protopic and Levaquin drug interactions.

What are the common drug interactions of Protopic and Levaquin, by gender? *:

female:

Deafness
Arthralgia (joint pain)
Back pain
Cheilitis (infection of lips)
Chest pain
Constipation
Fatigue (feeling of tiredness)
Gait disturbance
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypoaesthesia (reduced sense of touch or sensation)

male:

Anaemia (lack of blood)
Back pain
Osteonecrosis of jaw (death of bone of jaw)
Pain in jaw
Renal cyst (kidney cyst)
Tooth disorder (tooth disease)
Inflammation
Intervertebral disc protrusion (spinal disc protrusion)
Lumbar spine flattening (flatten the curve of the lower spine)
Mitral valve incompetence (inefficient heart valve)

What are the common drug interactions of Protopic and Levaquin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Chronic kidney disease
Emotional distress
Pain
Renal failure (kidney dysfunction)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Death
Decreased activity
Fear
Impaired work ability

30-39:

Blood cholesterol increased
Chest pain
Muscle spasms (muscle contraction)
Myalgia (muscle pain)
Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Hyperlipidaemia (presence of excess lipids in the blood)
Type 2 diabetes mellitus

40-49:

Dyspnoea (difficult or laboured respiration)
Tricuspid valve incompetence (inefficient heart valve)
Mitral valve incompetence (inefficient heart valve)
Abscess (pus)
Anaemia (lack of blood)
Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
Aortic calcification (aortic calcification sign of heart valve disease)
Aortic disorder
Arthralgia (joint pain)
Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)

50-59:

Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Renal impairment (severely reduced kidney function)
Type 2 diabetes mellitus
Urinary tract infection
Chronic kidney disease
Renal failure (kidney dysfunction)
Constipation
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Essential hypertension (primary hypertension)
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)

60+:

Anaemia (lack of blood)
Back pain
Pain in jaw
Tooth disorder (tooth disease)
Intervertebral disc protrusion (spinal disc protrusion)
Lumbar spine flattening (flatten the curve of the lower spine)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Renal cyst (kidney cyst)
Scoliosis (a medical condition in which a person's spine is curved from side to side)
Tendonitis (a condition that causes pain and swelling of tendons)

What are the existing conditions these people have? *

High Blood Pressure: 14 people, 31.11%
Metastasis (spreadable cancer to other organ from origin): 8 people, 17.78%
Pain: 4 people, 8.89%
Hiv Infection: 4 people, 8.89%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 6.67%
Bipolar Disorder (mood disorder): 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Protopic and Levaquin?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously