Provera and Breo ellipta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Provera (medroxyprogesterone acetate) and Breo ellipta (fluticasone furoate; vilanterol trifenatate). Common drug interactions include blood glucose increased among females.

The phase IV clinical study analyzes what interactions people have when they take Provera and Breo ellipta. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Provera?

Provera has active ingredients of medroxyprogesterone acetate. It is often used in birth control. eHealthMe is studying from 54,943 Provera users. Check the latest studies of Provera.

What is Breo ellipta?

Breo ellipta has active ingredients of fluticasone furoate; vilanterol trifenatate. It is often used in asthma. eHealthMe is studying from 37,362 Breo ellipta users. Check the latest studies of Breo ellipta.



On Jul, 10, 2026

16 people who take Provera and Breo ellipta together, and have interactions are studied.

Provera and Breo ellipta drug interactions.

What are the common drug interactions of Provera and Breo Ellipta, by gender? *:

female:

  1. Blood glucose increased
  2. Anxiety
  3. Pregnancy with implant contraceptive
  4. Unintended pregnancy (unwanted pregnancies as well as those that are mistimed)
  5. Blood sodium decreased
  6. Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
  7. Chest pain
  8. Clumsiness (a lack of coordination or elegance)
  9. Depression
  10. Dyspnoea (difficult or laboured respiration)

male:

n/a

What are the common drug interactions of Provera and Breo Ellipta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Eye pruritus (eye itching)
  2. Injection site discomfort

20-29:

n/a

30-39:

  1. Abortion spontaneous (naturally occurring miscarriage)
  2. Aspartate aminotransferase decreased
  3. Blood glucose increased
  4. Cystitis (inflammation of the wall of the bladder)
  5. Drug ineffective
  6. Pregnancy with implant contraceptive
  7. Unintended pregnancy (unwanted pregnancies as well as those that are mistimed)

40-49:

  1. Dyspnoea (difficult or laboured respiration)
  2. Obesity (having too much body fat)
  3. Obstructive airways disorder (a progressive disease that makes it hard to breathe)
  4. Pain
  5. Pruritus (severe itching of the skin)
  6. Somnolence (a state of near-sleep, a strong desire for sleep)
  7. Urticaria (rash of round, red welts on the skin that itch intensely)
  8. Anxiety
  9. Chronic kidney disease
  10. Forced expiratory volume decreased (decreased lung expired air volume)

50-59:

n/a

60+:

  1. Blood glucose increased
  2. Blood sodium decreased
  3. Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
  4. Ear infection
  5. Vomiting

What are the existing conditions these people have? *

  1. Thyroid Diseases: 3 people, 18.75%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 18.75%
  3. Indigestion: 2 people, 12.50%
  4. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 12.50%
  5. Diabetes: 2 people, 12.50%
  6. Fibromyalgia (a long-term condition which causes pain all over the body): 2 people, 12.50%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 12.50%
  8. High Blood Cholesterol: 2 people, 12.50%
  9. Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 2 people, 12.50%
  10. Hypokalemia (low potassium): 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Provera and Breo ellipta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Provera:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Breo ellipta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Provera and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Breo ellipta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on medroxyprogesterone acetate and fluticasone furoate; vilanterol trifenatate (the active ingredients of Provera and Breo ellipta, respectively), and Provera and Breo ellipta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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