Provera and Serophene drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Provera (medroxyprogesterone acetate) and Serophene (clomiphene citrate). Common drug interactions include arthralgia among females.
The phase IV clinical study analyzes what interactions people have when they take Provera and Serophene. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.
What is Provera?
Provera has active ingredients of medroxyprogesterone acetate. It is often used in birth control. eHealthMe is studying from 54,943 Provera users. Check the latest studies of Provera.
What is Serophene?
Serophene has active ingredients of clomiphene citrate. eHealthMe is studying from 241 Serophene users. Check the latest studies of Serophene.
15 people who take Provera and Serophene together, and have interactions are studied.

What are the common drug interactions of Provera and Serophene, by gender? *:
female:
- Arthralgia (joint pain)
- Blood pressure fluctuation
- Dizziness
- Fallopian tube disorder (fallopian tube disease)
- Fatigue (feeling of tiredness)
- Foot deformity (functional disability of foot)
- Heart rate increased
- Hypoaesthesia (reduced sense of touch or sensation)
- Hypotension (abnormally low blood pressure)
- Infertility
male:
n/a
What are the common drug interactions of Provera and Serophene, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Arthralgia (joint pain)
- Blood pressure fluctuation
- Dizziness
- Fallopian tube disorder (fallopian tube disease)
- Fatigue (feeling of tiredness)
- Foot deformity (functional disability of foot)
- Heart rate increased
- Hypoaesthesia (reduced sense of touch or sensation)
- Hypotension (abnormally low blood pressure)
- Infertility
40-49:
n/a
50-59:
n/a
60+:
n/a
What are the existing conditions these people have? *
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 13 people, 86.67%
- High Blood Pressure: 13 people, 86.67%
- Joint Pain: 4 people, 26.67%
- Anovulatory Cycle (menstrual cycle during which the ovaries do not release an oocyte): 1 person, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Provera and Serophene?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Provera and Serophene:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Provera:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Serophene:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Provera and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Serophene and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Bahall M, Reyes AJ, Ramcharan K, Hosein N, Seegobin K, Bahall K, Sharma H, Dhansingh S, Mahabir A, "Neuro-ophthalmological manifestations after intramuscular medroxyprogesterone: a forme fruste of idiopathic intracranial hypertension?", Neurology international, 2016 Sep .
- Bahall M, Reyes AJ, Ramcharan K, Hosein N, Seegobin K, Bahall K, Sharma H, Dhansingh S, Mahabir A, "Neuro-ophthalmological manifestations after intramuscular medroxyprogesterone: a forme fruste of idiopathic intracranial hypertension?", Neurology international, 2016 Sep .
How the study uses the data?
The study uses data from the FDA. It is based on medroxyprogesterone acetate and clomiphene citrate (the active ingredients of Provera and Serophene, respectively), and Provera and Serophene (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Could Adakveo cause Paraesthesia? - 11 seconds ago
- Drug interactions of Vitamin E and Wixela Inhub - 18 seconds ago
- Drug interactions of Advair Diskus 250/50 and Celexa - 19 seconds ago
- Drug interactions of Oxbryta and Valacyclovir - 24 seconds ago
- Could Epinastine Hydrochloride cause Diarrhea Aggravated? - 27 seconds ago
- Could Ancef cause Organ Failure? - 28 seconds ago
- Could Purinethol cause Acne? - 35 seconds ago
- Could Venofer cause Swollen Tongue? - 35 seconds ago
- Could Prednisone cause White Blood Cell Count Abnormal? - 39 seconds ago
- Could Ramipril cause Breast Cyst? - 40 seconds ago