Provigil and Probiotics drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Provigil (modafinil) and Probiotics (yogurt). Common drug interactions include drug ineffective among females and loss of consciousness among males.

The phase IV clinical study analyzes what interactions people have when they take Provigil and Probiotics. It is created by eHealthMe based on reports of 30 people who take the same drugs from the FDA, and is updated regularly.

What is Provigil?

Provigil has active ingredients of modafinil. It is often used in narcolepsy. eHealthMe is studying from 25,230 Provigil users. Check the latest studies of Provigil.

What is Probiotics?

Probiotics has active ingredients of yogurt. It is often used in irritable bowel syndrome. eHealthMe is studying from 9,541 Probiotics users. Check the latest studies of Probiotics.



On Jul, 20, 2026

30 people who take Provigil and Probiotics together, and have interactions are studied.

Provigil and Probiotics drug interactions.

What are the common drug interactions of Provigil and Probiotics, by gender? *:

female:

  1. Drug ineffective
  2. Depression
  3. Mobility decreased (ability to move is reduced)
  4. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  5. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  6. Diarrhoea
  7. Hypertension (high blood pressure)
  8. Muscle spasms (muscle contraction)
  9. Muscular weakness (muscle weakness)
  10. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)

male:

  1. Loss of consciousness
  2. Angiotensin converting enzyme increased
  3. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  4. Obstructive sleep apnoea syndrome (frequent pauses in breathing during sleep usually accompanied by loud snoring)
  5. Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
  6. Postural orthostatic tachycardia syndrome (abnormal increase in heart rate on becoming upright)
  7. Red blood cell sedimentation rate increased
  8. Vision blurred
  9. Vocal cord disorder
  10. Weight increased

What are the common drug interactions of Provigil and Probiotics, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Cough
  2. Depression
  3. Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain)
  4. Hypermobility syndrome (abnormalities cause abnormal stress on a joint or many joint)
  5. Muscle spasms (muscle contraction)
  6. Suicide attempt
  7. Surgery

40-49:

  1. Atrophic vulvovaginitis (inflammation of the vulva)
  2. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  3. Osteonecrosis (death of bone)
  4. Pain
  5. Arthralgia (joint pain)
  6. Asthma
  7. Back pain
  8. Blood sodium decreased
  9. Cataplexy (loss of muscle tone accompanied by full conscious awareness)
  10. Coeliac disease (simple food intolerance)

50-59:

  1. Sinusitis (inflammation of sinus)
  2. Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  3. Nasopharyngitis (inflammation of the nasopharynx)
  4. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  5. Diarrhoea
  6. Headache (pain in head)

60+:

  1. Abdominal distension
  2. Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)
  3. Drug ineffective
  4. Early satiety (feeling full before completing a normal sized meal)
  5. Metastases to peritoneum (cancer spreads to peritoneum)

What are the existing conditions these people have? *

  1. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 14 people, 46.67%
  2. Drowsiness: 12 people, 40.00%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 11 people, 36.67%
  4. High Blood Pressure: 3 people, 10.00%
  5. Type 2 Diabetes: 2 people, 6.67%
  6. Stable Angina (a constant chest pain): 2 people, 6.67%
  7. Sinus Disorder (disease of sinus): 2 people, 6.67%
  8. Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 2 people, 6.67%
  9. Migraine (headache): 2 people, 6.67%
  10. Immunodeficiency Common Variable: 2 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Provigil and Probiotics?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Provigil and Probiotics:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Provigil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Probiotics:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Provigil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Probiotics and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on modafinil and yogurt (the active ingredients of Provigil and Probiotics, respectively), and Provigil and Probiotics (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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