Prozac and Vancomycin hcl drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prozac (fluoxetine hydrochloride) and Vancomycin hcl (vancomycin hydrochloride). Common drug interactions include pruritus among females and drug hypersensitivity among males.

The phase IV clinical study analyzes what interactions people have when they take Prozac and Vancomycin hcl. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Prozac?

Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 82,981 Prozac users. Check the latest studies of Prozac.

What is Vancomycin hcl?

Vancomycin hcl has active ingredients of vancomycin hydrochloride. It is often used in clostridium difficile colitis. eHealthMe is studying from 6,530 Vancomycin hcl users. Check the latest studies of Vancomycin hcl.



On Feb, 25, 2026

28 people who take Prozac and Vancomycin hcl together, and have interactions are studied.

Prozac and Vancomycin hcl drug interactions.

What are the common drug interactions of Prozac and Vancomycin Hcl, by gender? *:

female:

  1. Pruritus (severe itching of the skin)
  2. Drug hypersensitivity
  3. Pyrexia (fever)
  4. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  5. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  6. Blood culture positive
  7. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  8. Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
  9. Dermatitis exfoliative generalised (inflammatory skin disease with erythema and scaling that affects nearly the entire cutaneous surface)
  10. Diarrhoea

male:

  1. Drug hypersensitivity
  2. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  3. Renal injury (kidney injury)
  4. Blood alkaline phosphatase increased
  5. Blood creatinine increased
  6. Burning sensation
  7. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  8. Glomerular filtration rate decreased
  9. Hypoglycaemia (deficiency of glucose in the bloodstream)
  10. Irritability

What are the common drug interactions of Prozac and Vancomycin Hcl, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Blood alkaline phosphatase increased
  2. Burning sensation
  3. Drug hypersensitivity
  4. Irritability
  5. Joint injury
  6. Limb injury
  7. Road traffic accident

40-49:

  1. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  2. Drug hypersensitivity
  3. Hypoglycaemia (deficiency of glucose in the bloodstream)
  4. Renal failure chronic (long lasting kidney dysfunction)

50-59:

  1. Pruritus (severe itching of the skin)
  2. Drug hypersensitivity
  3. Pyrexia (fever)
  4. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  5. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  6. Blood culture positive
  7. Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
  8. Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
  9. Dermatitis exfoliative generalised (inflammatory skin disease with erythema and scaling that affects nearly the entire cutaneous surface)
  10. Diarrhoea

60+:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Death
  3. Blood creatinine increased
  4. Glomerular filtration rate decreased
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  7. Renal disorder (kidney disease)
  8. Emotional distress
  9. Fear
  10. Injury

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 28.57%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 7 people, 25.00%
  3. Inflammation: 2 people, 7.14%
  4. Fever: 2 people, 7.14%
  5. Arteriovenous Fistula Thrombosis (formation of a blood clot inside a blood vessel-av fistula): 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Prozac and Vancomycin hcl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prozac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Vancomycin hcl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prozac and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vancomycin hcl and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on fluoxetine hydrochloride and vancomycin hydrochloride (the active ingredients of Prozac and Vancomycin hcl, respectively), and Prozac and Vancomycin hcl (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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