Prozac and Xulane drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prozac (fluoxetine hydrochloride) and Xulane (ethinyl estradiol; norelgestromin). Common drug interactions include drug ineffective among females.

The phase IV clinical study analyzes what interactions people have when they take Prozac and Xulane. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Prozac?

Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 82,988 Prozac users. Check the latest studies of Prozac.

What is Xulane?

Xulane has active ingredients of ethinyl estradiol; norelgestromin. It is often used in birth control. eHealthMe is studying from 1,756 Xulane users. Check the latest studies of Xulane.

On Jul, 18, 2026

11 people who take Prozac and Xulane together, and have interactions are studied.

What are the common drug interactions of Prozac and Xulane, by gender? *:

female:

Drug ineffective
Disturbance in attention
Post-traumatic stress disorder
Weight fluctuation
Adverse drug reaction
Application site erythema (redness of the skin at application site)
Application site pain
Application site pruritus (application site severe itching of the skin)
Hypophagia (reduced food intake)
Sinusitis (inflammation of sinus)

male:

n/a

What are the common drug interactions of Prozac and Xulane, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Abdominal discomfort
Diarrhoea
Nausea (feeling of having an urge to vomit)
Adverse drug reaction
Hypophagia (reduced food intake)
Hypersomnia (excessive daytime sleepiness (eds))
Seizure (abnormal excessive or synchronous neuronal activity in the brain)

20-29:

Feeling drunk
Nasopharyngitis (inflammation of the nasopharynx)
Post-traumatic stress disorder
Weight fluctuation

30-39:

Application site erythema (redness of the skin at application site)
Application site pain
Application site pruritus (application site severe itching of the skin)

40-49:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)

50-59:

n/a

60+:

n/a

What are the existing conditions these people have? *

Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract): 4 people, 36.36%
Short-Bowel Syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing): 3 people, 27.27%
Nausea (feeling of having an urge to vomit): 3 people, 27.27%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 27.27%
Functional Gastrointestinal Disorder (functional problem in separate organs of gastrointestinal system): 2 people, 18.18%
Constipation: 2 people, 18.18%
Diarrhea: 2 people, 18.18%
Drooling (drop saliva uncontrollably from the mouth): 2 people, 18.18%
Drowsiness: 2 people, 18.18%
Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

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