Psyllium and Atarax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Psyllium (blond psyllium) and Atarax (hydroxyzine hydrochloride). Common drug interactions include chronic myeloid leukaemia among females and agranulocytosis among males.

The phase IV clinical study analyzes what interactions people have when they take Psyllium and Atarax. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Psyllium?

Psyllium has active ingredients of blond psyllium. It is often used in constipation. eHealthMe is studying from 4,262 Psyllium users. Check the latest studies of Psyllium.

What is Atarax?

Atarax has active ingredients of hydroxyzine hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 23,553 Atarax users. Check the latest studies of Atarax.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 20, 2026

12 people who take Psyllium and Atarax together, and have interactions are studied.

Psyllium and Atarax drug interactions.

What are the common drug interactions of Psyllium and Atarax, by gender? *:

female:

  1. Chronic myeloid leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood)
  2. Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
  3. Ischaemic ulcer (arterial ulcer)
  4. Malignant neoplasm progression (cancer tumour came back)
  5. Pain in extremity
  6. Peripheral vascular disorder
  7. Sudden cardiac death
  8. Vascular insufficiency
  9. Alanine aminotransferase increased
  10. Body height decreased

male:

  1. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
  2. Fall
  3. Renal cyst (kidney cyst)
  4. Upper limb fracture

What are the common drug interactions of Psyllium and Atarax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)

60+:

  1. Weight fluctuation
  2. Bradycardia (abnormally slow heart action)
  3. Dyspnoea (difficult or laboured respiration)
  4. Fall
  5. Hyperkalaemia (damage to or disease of the kidney)
  6. Hypotension (abnormally low blood pressure)
  7. Overdose
  8. Renal cyst (kidney cyst)
  9. Upper limb fracture
  10. Chest pain

What are the existing conditions these people have? *

  1. Pain: 6 people, 50.00%
  2. Itching: 5 people, 41.67%
  3. Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 33.33%
  4. Interstitial Lung Disease: 4 people, 33.33%
  5. Systemic Sclerosis (Scleroderma) (an autoimmune or connective tissue disease. it is characterized by thickening of the skin): 4 people, 33.33%
  6. High Blood Pressure: 4 people, 33.33%
  7. Diarrhea: 4 people, 33.33%
  8. Pulmonary Hypertension (increase in blood pressure in the lung artery): 4 people, 33.33%
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 25.00%
  10. Depression: 3 people, 25.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Psyllium and Atarax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Psyllium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Atarax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Psyllium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Atarax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on blond psyllium and hydroxyzine hydrochloride (the active ingredients of Psyllium and Atarax, respectively), and Psyllium and Atarax (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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