Psyllium and Medrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Psyllium (blond psyllium) and Medrol (methylprednisolone). Common drug interactions include productive cough among females and somnolence among males.

The phase IV clinical study analyzes what interactions people have when they take Psyllium and Medrol. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Psyllium?

Psyllium has active ingredients of blond psyllium. It is often used in constipation. eHealthMe is studying from 4,262 Psyllium users. Check the latest studies of Psyllium.

What is Medrol?

Medrol has active ingredients of methylprednisolone. It is often used in rheumatoid arthritis. eHealthMe is studying from 24,443 Medrol users. Check the latest studies of Medrol.



On Jul, 06, 2026

28 people who take Psyllium and Medrol together, and have interactions are studied.

Psyllium and Medrol drug interactions.

What are the common drug interactions of Psyllium and Medrol, by gender? *:

female:

  1. Productive cough
  2. Pyrexia (fever)
  3. Chills (felling of cold)
  4. Drug ineffective
  5. Drug intolerance (drug sensitivity)
  6. Muscular weakness (muscle weakness)
  7. Pneumonia

male:

  1. Somnolence (a state of near-sleep, a strong desire for sleep)
  2. Dyspnoea (difficult or laboured respiration)
  3. Pain
  4. Pain in extremity
  5. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  6. Testicular swelling (swelling of testes)
  7. Weight decreased
  8. Abdominal pain upper
  9. Anaemia (lack of blood)
  10. Anxiety

What are the common drug interactions of Psyllium and Medrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Pneumonia
  2. Productive cough
  3. Pyrexia (fever)
  4. Testicular swelling (swelling of testes)
  5. Abdominal pain upper
  6. Anaemia (lack of blood)
  7. Anxiety
  8. Arteriosclerosis (thickening and hardening of arteries)
  9. Arthralgia (joint pain)
  10. Asthenia (weakness)

60+:

  1. Arthralgia (joint pain)
  2. Cardiac failure congestive
  3. Somnolence (a state of near-sleep, a strong desire for sleep)
  4. Weight decreased
  5. Abdominal pain upper
  6. Accelerated hypertension (significant hypertension)
  7. Acne (skin problems that cause pimples)
  8. Alopecia (absence of hair from areas of the body)
  9. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  10. Anaemia (lack of blood)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 12 people, 42.86%
  2. Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 5 people, 17.86%
  3. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 14.29%
  4. Pain: 2 people, 7.14%
  5. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Psyllium and Medrol?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Psyllium and Medrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Psyllium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Medrol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Psyllium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Medrol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on blond psyllium and methylprednisolone (the active ingredients of Psyllium and Medrol, respectively), and Psyllium and Medrol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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