Psyllium and Topamax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Psyllium (blond psyllium) and Topamax (topiramate). Common drug interactions include intervertebral disc disorder among females and intervertebral disc protrusion among males.

The phase IV clinical study analyzes what interactions people have when they take Psyllium and Topamax. It is created by eHealthMe based on reports of 32 people who take the same drugs from the FDA, and is updated regularly.

What is Psyllium?

Psyllium has active ingredients of blond psyllium. It is often used in constipation. eHealthMe is studying from 4,262 Psyllium users. Check the latest studies of Psyllium.

What is Topamax?

Topamax has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 58,954 Topamax users. Check the latest studies of Topamax.

On Jul, 17, 2026

32 people who take Psyllium and Topamax together, and have interactions are studied.

What are the common drug interactions of Psyllium and Topamax, by gender? *:

female:

Intervertebral disc disorder (spinal disc disorder)
Joint dislocation (a joint position is changed from normal position)
Joint injury
Lichen planus (an inflammatory skin condition, characterized by an itchy, non-infectious rash)
Limb injury
Localised infection (infection at the single location)
Malaise (a feeling of general discomfort or uneasiness)
Nasal septum deviation (deviated nasal septum)
Respiratory disorder (respiratory disease)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)

male:

Intervertebral disc protrusion (spinal disc protrusion)
Pain
Asthenia (weakness)
Back disorder
Back pain
Burning sensation
Chronic kidney disease
Decreased activity
Depression
Dizziness postural

What are the common drug interactions of Psyllium and Topamax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Cardiac disorder
Fatigue (feeling of tiredness)
Psychomotor hyperactivity (feelings of extreme restlessness)
Somnolence (a state of near-sleep, a strong desire for sleep)

20-29:

Aggression

30-39:

Abnormal behaviour
Aggression
Agitation (state of anxiety or nervous excitement)
Chronic kidney disease
Hallucination, auditory (perceiving sounds without auditory stimulus)
Renal failure (kidney dysfunction)
Suicidal behaviour
Toothache (tooth pain)

40-49:

Fatigue (feeling of tiredness)
Headache (pain in head)
Lymphopenia (an abnormally low level of lymphocytes in the blood)
Meningitis aseptic (a condition that causes the membranes covering your brain and spinal cord to become inflamed)
Nausea (feeling of having an urge to vomit)
Neck pain
Renal pain (kidney pain)
Stress
White blood cell count increased
Insomnia (sleeplessness)

50-59:

Pain
Sinusitis (inflammation of sinus)
Depression
Diarrhoea
Intervertebral disc protrusion (spinal disc protrusion)
Abdominal pain
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Ankle fracture
Anxiety

60+:

Hair colour changes
Impaired healing
Lichen planus (an inflammatory skin condition, characterized by an itchy, non-infectious rash)

What are the existing conditions these people have? *

Nausea (feeling of having an urge to vomit): 9 people, 28.12%
Immunodeficiency Common Variable: 9 people, 28.12%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 8 people, 25.00%
Headache (pain in head): 8 people, 25.00%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 8 people, 25.00%
Pain: 7 people, 21.88%
Skin Blushing/flushing (a sudden reddening of the face, neck): 6 people, 18.75%
Primary Immunodeficiency Syndrome: 3 people, 9.38%
Lymphoproliferative Disorder (a medical condition in which the immune system makes too many white blood cells): 3 people, 9.38%
Sleep Disorder: 2 people, 6.25%

* Approximation only. Some reports may have incomplete information.

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