Psyllium and Zometa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Psyllium (blond psyllium) and Zometa (zoledronic acid). Common drug interactions include chest pain among females and osteonecrosis of jaw among males.

The phase IV clinical study analyzes what interactions people have when they take Psyllium and Zometa. It is created by eHealthMe based on reports of 76 people who take the same drugs from the FDA, and is updated regularly.

What is Psyllium?

Psyllium has active ingredients of blond psyllium. It is often used in constipation. eHealthMe is studying from 4,262 Psyllium users. Check the latest studies of Psyllium.

What is Zometa?

Zometa has active ingredients of zoledronic acid. It is often used in multiple myeloma. eHealthMe is studying from 71,434 Zometa users. Check the latest studies of Zometa.

On Jul, 11, 2026

76 people who take Psyllium and Zometa together, and have interactions are studied.

What are the common drug interactions of Psyllium and Zometa, by gender? *:

female:

Chest pain
Colonic stenosis (abnormal narrowing of colon)
Deformity (disfigurement)
Depression
Dyspnoea exertional (breathlessness or shortness of breath)
Emotional distress
Erythema (redness of the skin)
Exposed bone in jaw
Facial nerve disorder (disease of face nerve)
Facial pain

male:

Osteonecrosis of jaw (death of bone of jaw)
Osteomyelitis (infection of bone)
Pleural effusion (water on the lungs)
General physical health deterioration (weak health status)
Injury
Nausea (feeling of having an urge to vomit)
Vomiting
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Productive cough
Spinal osteoarthritis (joint cartilage loss in spine)

What are the common drug interactions of Psyllium and Zometa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Acute myocardial infarction (acute heart attack)
Anaemia (lack of blood)
Anxiety
Arthralgia (joint pain)
Asthenia (weakness)
Atelectasis (partial or complete collapse of the lung)
Back pain
Bone disorder
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cerebral haemorrhage (bleeding within the brain)

50-59:

Cardiac failure congestive
Diarrhoea
Dizziness
General physical health deterioration (weak health status)
Hyperlipidaemia (presence of excess lipids in the blood)
Hypoaesthesia (reduced sense of touch or sensation)
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hypotension (abnormally low blood pressure)
Infection
Injury

60+:

Osteonecrosis of jaw (death of bone of jaw)
Diarrhoea
Osteomyelitis (infection of bone)
Abdominal distension
Acute sinusitis
Blood creatinine increased
Blood urea increased
Gout (uric acid crystals building up in the body)
Impaired healing
Skin oedema (swelling of skin)

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 14 people, 18.42%
Metastases To Bone (cancer spreads to bone): 14 people, 18.42%
Bone Loss: 14 people, 18.42%
Sleep Disorder: 12 people, 15.79%
Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 10 people, 13.16%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 10 people, 13.16%
High Blood Pressure: 10 people, 13.16%
Nausea (feeling of having an urge to vomit): 9 people, 11.84%
Chronic Kidney Disease: 8 people, 10.53%
Arrhythmias (irregular heartbeat): 8 people, 10.53%

* Approximation only. Some reports may have incomplete information.

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