Pulmicort flexhaler and Centrum drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pulmicort flexhaler (budesonide) and Centrum (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e). Common drug interactions include dysphonia among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Pulmicort flexhaler and Centrum. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Pulmicort flexhaler?

Pulmicort flexhaler has active ingredients of budesonide. It is often used in asthma. eHealthMe is studying from 5,527 Pulmicort flexhaler users. Check the latest studies of Pulmicort flexhaler.

What is Centrum?

Centrum has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. It is often used in vitamin supplementation. eHealthMe is studying from 34,686 Centrum users. Check the latest studies of Centrum.



On Jul, 09, 2026

18 people who take Pulmicort flexhaler and Centrum together, and have interactions are studied.

Pulmicort flexhaler and Centrum drug interactions.

What are the common drug interactions of Pulmicort Flexhaler and Centrum, by gender? *:

female:

  1. Dysphonia (speech disorder attributable to a disorder of phonation)
  2. Lung disorder (lung disease)
  3. Organising pneumonia (pathologically by the presence in the distal air spaces of buds of granulation tissue)
  4. Visual impairment
  5. Cheilitis (infection of lips)
  6. Cough
  7. Drug ineffective
  8. Dyspnoea (difficult or laboured respiration)
  9. Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone)
  10. Arthritis (form of joint disorder that involves inflammation of one or more joints)

male:

  1. Drug ineffective
  2. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  3. Stress at work
  4. Nasopharyngitis (inflammation of the nasopharynx)
  5. Peptic ulcer
  6. Diarrhoea
  7. Insomnia (sleeplessness)
  8. Alopecia (absence of hair from areas of the body)
  9. Herpes zoster
  10. Nasal septum deviation (deviated nasal septum)

What are the common drug interactions of Pulmicort Flexhaler and Centrum, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Abdominal pain upper
  2. Dysstasia (difficulty in standing)
  3. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  4. Pain
  5. Spinal disorder (disease of spine a back bone)
  6. Ulcer

60+:

  1. Dysphonia (speech disorder attributable to a disorder of phonation)
  2. Lung disorder (lung disease)
  3. Nasopharyngitis (inflammation of the nasopharynx)
  4. Pharyngitis (inflammation of the pharynx, causing a sore throat)
  5. Alopecia (absence of hair from areas of the body)
  6. Dry mouth
  7. Dry throat
  8. Gastroenteritis (inflammation of stomach and intestine)
  9. Haematuria (presence of blood in urine)
  10. Heart rate increased

What are the existing conditions these people have? *

  1. Dyspnea (difficult or laboured breathing): 7 people, 38.89%
  2. Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 5 people, 27.78%
  3. Cardiac Disorder: 5 people, 27.78%
  4. Fluid Retention (an abnormal accumulation of fluid in the blood): 4 people, 22.22%
  5. High Blood Cholesterol: 4 people, 22.22%
  6. Lung Disorder (lung disease): 4 people, 22.22%
  7. Heart Rate Irregular: 3 people, 16.67%
  8. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 16.67%
  9. Vitamin D Decreased: 2 people, 11.11%
  10. Blood Pressure Abnormal: 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

Do you take Pulmicort flexhaler and Centrum?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Pulmicort flexhaler and Centrum:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pulmicort flexhaler:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Centrum:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Pulmicort flexhaler and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Centrum and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on budesonide and ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e (the active ingredients of Pulmicort flexhaler and Centrum, respectively), and Pulmicort flexhaler and Centrum (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: