Pyrazinamide and Sertraline drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pyrazinamide (pyrazinamide) and Sertraline (sertraline hydrochloride). Common drug interactions include anaemia among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Pyrazinamide and Sertraline. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.

What is Pyrazinamide?

Pyrazinamide has active ingredients of pyrazinamide. It is often used in tuberculosis. eHealthMe is studying from 10,062 Pyrazinamide users. Check the latest studies of Pyrazinamide.

What is Sertraline?

Sertraline has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 153,304 Sertraline users. Check the latest studies of Sertraline.

On Jul, 06, 2026

18 people who take Pyrazinamide and Sertraline together, and have interactions are studied.

Pyrazinamide and Sertraline drug interactions.

What are the common drug interactions of Pyrazinamide and Sertraline, by gender? *:

female:

Anaemia (lack of blood)
Electrocardiogram qt prolonged
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hypokalaemia (low potassium)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Vomiting
Adjustment disorder with depressed mood
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Diarrhoea

male:

Pain
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Burning sensation
Chest pain
Chronic kidney disease
Drug hypersensitivity
Eosinophil count increased
Hypersensitivity
Impaired healing
Local swelling (swelling at the site of some application of substance or injury)

What are the common drug interactions of Pyrazinamide and Sertraline, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Drug hypersensitivity
Eosinophil count increased
Long qt syndrome (disorder of the heart's electrical system)
Rash

30-39:

Face oedema (swelling of face)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
Visual impairment

40-49:

Anaemia (lack of blood)
Electrocardiogram qt prolonged
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Hypokalaemia (low potassium)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Vomiting
Adjustment disorder with depressed mood
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Diarrhoea

50-59:

Burning sensation
Chest pain
Hypersensitivity
Impaired healing
Local swelling (swelling at the site of some application of substance or injury)
Loss of consciousness
Mass
Pain
Pneumonia
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)

60+:

Alanine aminotransferase increased
Aspartate aminotransferase increased
White blood cell count increased
Asthenia (weakness)
Asthma
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Lower respiratory tract infection
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
Platelet count increased

What are the existing conditions these people have? *

High Blood Pressure: 5 people, 27.78%
Diabetes: 4 people, 22.22%
Hiv Infection: 3 people, 16.67%
Adjustment Disorder With Depressed Mood: 3 people, 16.67%
Nausea And Vomiting: 3 people, 16.67%
Hypokalemia (low potassium): 2 people, 11.11%
Anaemia (lack of blood): 2 people, 11.11%
Pneumonia: 2 people, 11.11%
Ill-Defined Disorder: 2 people, 11.11%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 2 people, 11.11%

* Approximation only. Some reports may have incomplete information.

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