Pyrazinamide and Viread drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Pyrazinamide (pyrazinamide) and Viread (tenofovir disoproxil fumarate). Common drug interactions include drug level increased among females and renal failure among males.

The phase IV clinical study analyzes what interactions people have when they take Pyrazinamide and Viread. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Pyrazinamide?

Pyrazinamide has active ingredients of pyrazinamide. It is often used in tuberculosis. eHealthMe is studying from 10,062 Pyrazinamide users. Check the latest studies of Pyrazinamide.

What is Viread?

Viread has active ingredients of tenofovir disoproxil fumarate. It is often used in hepatitis b. eHealthMe is studying from 51,542 Viread users. Check the latest studies of Viread.

On Jul, 12, 2026

40 people who take Pyrazinamide and Viread together, and have interactions are studied.

Pyrazinamide and Viread drug interactions.

What are the common drug interactions of Pyrazinamide and Viread, by gender? *:

female:

Drug level increased
Nausea (feeling of having an urge to vomit)
Pulmonary tuberculosis (lungs tuberculosis)
Sleep disorder
Transaminases increased
Vomiting
Depression
Hepatic failure (liver failure)
Herpes virus infection
Hypophagia (reduced food intake)

male:

Renal failure (kidney dysfunction)
Anaemia (lack of blood)
Drug eruption (adverse drug reaction of the skin)
Emotional distress
Hepatotoxicity (chemical-driven liver damage)
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Leukopenia (less number of white blood cells in blood)
Nephropathy (damage to or disease of a kidney)
Pain
Pyrexia (fever)

What are the common drug interactions of Pyrazinamide and Viread, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Nausea (feeling of having an urge to vomit)
Platelet count decreased
Drug level increased
Pulmonary tuberculosis (lungs tuberculosis)
Sleep disorder
Transaminases increased
Vomiting
Alanine aminotransferase increased
Aspartate aminotransferase increased
Pyrexia (fever)

30-39:

Sepsis (a severe blood infection that can lead to organ failure and death)
Anaemia (lack of blood)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Coma (state of unconsciousness lasting more than six hours)
Hepatotoxicity (chemical-driven liver damage)
Hyperuricaemia (level of uric acid in the blood that is abnormally high)
Immune reconstitution syndrome (immune recovery syndrome)
Renal failure acute (rapid kidney dysfunction)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Depression

40-49:

Chronic kidney disease
Emotional distress
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Hepatic failure (liver failure)
Multiple fractures
Nephropathy (damage to or disease of a kidney)
Pain
Renal atrophy (wasting of kidney)
Renal failure (kidney dysfunction)
Rib fracture

50-59:

Drug eruption (adverse drug reaction of the skin)
Leukopenia (less number of white blood cells in blood)
Anaemia (lack of blood)
Aspartate aminotransferase increased
Ataxia (loss of full control of bodily movements)
Brain abscess
Confusional state
Death
Depressed level of consciousness
Disseminated tuberculosis

60+:

Abdominal pain upper
Asthenia (weakness)
Renal failure (kidney dysfunction)
Atrioventricular block complete (heart block complete)
Blood potassium increased
Bradycardia (abnormally slow heart action)
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Dizziness
Hypotension (abnormally low blood pressure)

What are the existing conditions these people have? *

Hiv Infection: 29 people, 72.50%
Pulmonary Tuberculosis (lungs tuberculosis): 6 people, 15.00%
Anaemia (lack of blood): 6 people, 15.00%
Acquired Immunodeficiency Syndrome (disease of the human immune system caused by the human immunodeficiency virus (hiv)): 5 people, 12.50%
Sinusitis (inflammation of sinus): 3 people, 7.50%
Pain: 2 people, 5.00%
Leukopenia (less number of white blood cells in blood): 2 people, 5.00%
Kaposi's Sarcoma Aids Related (a tumour caused by human herpes virus associated with aids): 2 people, 5.00%
Bladder Outlet Obstruction (urological condition where the urine flow from the urinary bladder through the urethra is impeded): 2 people, 5.00%
Acarodermatitis (skin inflammation caused by mites (acarids)): 2 people, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Pyrazinamide and Viread?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously