Questran and Codeine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Questran (cholestyramine) and Codeine (codeine sulfate). Common drug interactions include inflammatory bowel disease among females and nephrolithiasis among males.

The phase IV clinical study analyzes what interactions people have when they take Questran and Codeine. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Questran?

Questran has active ingredients of cholestyramine. It is often used in diarrhea. eHealthMe is studying from 4,490 Questran users. Check the latest studies of Questran.

What is Codeine?

Codeine has active ingredients of codeine sulfate. It is often used in pain. eHealthMe is studying from 42,342 Codeine users. Check the latest studies of Codeine.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

44 people who take Questran and Codeine together, and have interactions are studied.

What are the common drug interactions of Questran and Codeine, by gender? *:

female:

Inflammatory bowel disease
Dyspepsia (indigestion)
Furuncle (infection of the hair follicle)
Ascites (accumulation of fluid in the abdominal cavity)
Chronic kidney disease
Malaise (a feeling of general discomfort or uneasiness)
Metastases to liver (cancer spreads to liver)
Metastases to peritoneum (cancer spreads to peritoneum)
Pancreatic carcinoma metastatic (pancreatic cancer- metastatic)
Short-bowel syndrome (a condition in which the body cannot absorb enough fluids and nutrients because part of the small intestine is missing)

male:

Nephrolithiasis (calculi in the kidneys)
Hypertension (high blood pressure)
Pleural effusion (water on the lungs)
Pneumonia
Chronic kidney disease
Dementia (madness)
Dysphagia (a condition in which swallowing is difficult or painful)
Renal failure (kidney dysfunction)
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Communication disorder (speech and language disorder)

What are the common drug interactions of Questran and Codeine, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal pain
Abdominal pain upper
Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
Contusion (a type of hematoma of tissue in which capillaries)
Depression
Dyspepsia (indigestion)
Eye swelling
Furuncle (infection of the hair follicle)
Hypertension (high blood pressure)
Infusion related reaction

30-39:

n/a

40-49:

Inflammatory bowel disease
Chronic kidney disease
Dysphagia (a condition in which swallowing is difficult or painful)
Renal failure (kidney dysfunction)

50-59:

Bacteraemia (presence of bacteria in the blood)
Cardiac failure congestive
Iron deficiency anaemia
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Pleural effusion (water on the lungs)
Pneumonia

60+:

Nephrolithiasis (calculi in the kidneys)
Hypertension (high blood pressure)
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)
Body height decreased
Cataract (clouding of the lens inside the eye)
Cystoid macular oedema (fluid accumulation after cataract surgery)
Dyspepsia (indigestion)
Foot deformity (functional disability of foot)
Furuncle (infection of the hair follicle)
Herpes zoster

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 21 people, 47.73%
Osteoporosis (bones weak and more likely to break): 15 people, 34.09%
Cough: 14 people, 31.82%
Dyspnea (difficult or laboured breathing): 14 people, 31.82%
Headache (pain in head): 14 people, 31.82%
Nausea (feeling of having an urge to vomit): 13 people, 29.55%
Idiopathic Pulmonary Fibrosis (chronic lung disease): 13 people, 29.55%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 13 people, 29.55%
Hypotension (abnormally low blood pressure): 11 people, 25.00%
High Blood Pressure: 10 people, 22.73%

* Approximation only. Some reports may have incomplete information.

Do you take Questran and Codeine?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously