Questran and Fenofibrate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Questran (cholestyramine) and Fenofibrate (fenofibrate). Common drug interactions include alanine aminotransferase increased among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Questran and Fenofibrate. It is created by eHealthMe based on reports of 38 people who take the same drugs from the FDA, and is updated regularly.

What is Questran?

Questran has active ingredients of cholestyramine. It is often used in diarrhea. eHealthMe is studying from 4,490 Questran users. Check the latest studies of Questran.

What is Fenofibrate?

Fenofibrate has active ingredients of fenofibrate. It is often used in high blood cholesterol. eHealthMe is studying from 40,457 Fenofibrate users. Check the latest studies of Fenofibrate.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 26, 2026

38 people who take Questran and Fenofibrate together, and have interactions are studied.

Questran and Fenofibrate drug interactions.

What are the common drug interactions of Questran and Fenofibrate, by gender? *:

female:

Alanine aminotransferase increased
Anion gap increased
Asthenia (weakness)
Bacterial infection
Bacterial test positive
Blood alkaline phosphatase increased
Blood chloride increased
Blood glucose decreased
Brain injury
Carbon dioxide decreased

male:

Asthenia (weakness)
Headache (pain in head)
Anxiety
Application site pruritus (application site severe itching of the skin)
Application site rash
Bile duct obstruction (blockage in the tubes that carry bile from the liver to the gallbladder)
Blood bilirubin increased
Chest discomfort
Cholangiocarcinoma (a cancer that forms glands or secretes significant amounts of mucins)
Chronic kidney disease

What are the common drug interactions of Questran and Fenofibrate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Pain
Persecutory delusion
Renal failure (kidney dysfunction)
Stress
Throat tightness
Visual impairment
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Asthenia (weakness)
Chronic kidney disease

50-59:

Muscle cramps (painful sensations caused by muscle contraction)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Cholangiocarcinoma (a cancer that forms glands or secretes significant amounts of mucins)
Malaise (a feeling of general discomfort or uneasiness)
Metastatic lymphoma (spreadable cancer tumour of lymph node)
Nausea (feeling of having an urge to vomit)

60+:

Pyrexia (fever)
Abdominal pain lower
Drug level below therapeutic
Drug level decreased
Erythema (redness of the skin)
Gait disturbance
Groin pain
Malaise (a feeling of general discomfort or uneasiness)
Pain
Pruritus (severe itching of the skin)

What are the existing conditions these people have? *

Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 17 people, 44.74%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 10.53%
High Blood Pressure: 3 people, 7.89%
Stress And Anxiety: 2 people, 5.26%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 5.26%
Diabetes: 2 people, 5.26%
Depression: 2 people, 5.26%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 2 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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