Qulipta and Topamax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Qulipta (atogepant) and Topamax (topiramate). Common drug interactions include constipation among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Qulipta and Topamax. It is created by eHealthMe based on reports of 73 people who take the same drugs from the FDA, and is updated regularly.

What is Qulipta?

Qulipta has active ingredients of atogepant. eHealthMe is studying from 3,605 Qulipta users. Check the latest studies of Qulipta.

What is Topamax?

Topamax has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 58,954 Topamax users. Check the latest studies of Topamax.



On Jul, 12, 2026

73 people who take Qulipta and Topamax together, and have interactions are studied.

Qulipta and Topamax drug interactions.

What are the common drug interactions of Qulipta and Topamax, by gender? *:

female:

  1. Constipation
  2. Drug ineffective
  3. Headache (pain in head)
  4. Fatigue (feeling of tiredness)
  5. Arthralgia (joint pain)
  6. Asthenia (weakness)
  7. Pruritus (severe itching of the skin)
  8. Abdominal distension
  9. Decreased appetite
  10. Pain

male:

  1. Anxiety
  2. Arrhythmia (irregular heartbeat)
  3. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  4. Aura
  5. Nephrolithiasis (calculi in the kidneys)
  6. Pruritus (severe itching of the skin)
  7. Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
  8. Ventricular extrasystoles (premature cardiac contraction)
  9. Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)

What are the common drug interactions of Qulipta and Topamax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Memory impairment
  2. Weight increased
  3. Anxiety
  4. Aura
  5. Constipation
  6. Headache (pain in head)
  7. Nausea (feeling of having an urge to vomit)

30-39:

  1. Arthralgia (joint pain)
  2. Decreased appetite
  3. Weight decreased
  4. Drug hypersensitivity
  5. Eye disorder
  6. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
  7. Nausea (feeling of having an urge to vomit)

40-49:

  1. Nausea (feeling of having an urge to vomit)
  2. Nephrolithiasis (calculi in the kidneys)
  3. Blood pressure increased
  4. Headache (pain in head)
  5. Abdominal distension
  6. Abdominal pain upper
  7. Alopecia (absence of hair from areas of the body)
  8. Aphonia (inability to produce voice)
  9. Constipation
  10. Cystitis (inflammation of the wall of the bladder)

50-59:

  1. Pruritus (severe itching of the skin)
  2. Allergy to metals
  3. Arthritis (form of joint disorder that involves inflammation of one or more joints)
  4. Bacterial infection
  5. Bone pain
  6. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  7. Ear infection
  8. Ear infection bacterial
  9. Fatigue (feeling of tiredness)
  10. Hip fracture

60+:

  1. Death
  2. Dizziness
  3. Drug ineffective
  4. Headache (pain in head)
  5. Therapeutic response delayed (late preventive response)

What are the existing conditions these people have? *

  1. Stress And Anxiety: 4 people, 5.48%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 5.48%

* Approximation only. Some reports may have incomplete information.

Do you take Qulipta and Topamax?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Qulipta and Topamax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Qulipta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Topamax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Qulipta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Topamax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on atogepant and topiramate (the active ingredients of Qulipta and Topamax, respectively), and Qulipta and Topamax (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: