Rabeprazole and Epival drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rabeprazole (rabeprazole sodium) and Epival (divalproex sodium). Common drug interactions include breast pain among females and abdominal discomfort among males.

The phase IV clinical study analyzes what interactions people have when they take Rabeprazole and Epival. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Rabeprazole?

Rabeprazole has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 31,689 Rabeprazole users. Check the latest studies of Rabeprazole.

What is Epival?

Epival has active ingredients of divalproex sodium. It is often used in epilepsy. eHealthMe is studying from 1,088 Epival users. Check the latest studies of Epival.

On Jul, 11, 2026

16 people who take Rabeprazole and Epival together, and have interactions are studied.

Rabeprazole and Epival drug interactions.

What are the common drug interactions of Rabeprazole and Epival, by gender? *:

female:

Breast pain
Communication disorder (speech and language disorder)
Drug ineffective
Pain
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Stress
Abdominal discomfort
Dizziness
Dry mouth
Micturition urgency (urgency to pass the urine)

male:

Abdominal discomfort
Impaired healing
Lung neoplasm malignant (cancer tumour of lung)
Pleural effusion (water on the lungs)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Death
Endocarditis (inflammation in heart muscle)

What are the common drug interactions of Rabeprazole and Epival, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Endocarditis (inflammation in heart muscle)

50-59:

Impaired healing
Lung neoplasm malignant (cancer tumour of lung)
Pleural effusion (water on the lungs)
Death
Abdominal discomfort

60+:

Anxiety
Blood pressure increased
Breast pain
Communication disorder (speech and language disorder)
Drug ineffective
Headache (pain in head)
Pain
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Stress

What are the existing conditions these people have? *

Migraine (headache): 6 people, 37.50%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 6 people, 37.50%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 3 people, 18.75%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 18.75%
Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

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