Rabeprazole and Hepsera drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rabeprazole (rabeprazole sodium) and Hepsera (adefovir dipivoxil). Common drug interactions include blood parathyroid hormone increased among females and ascites among males.

The phase IV clinical study analyzes what interactions people have when they take Rabeprazole and Hepsera. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Rabeprazole?

Rabeprazole has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 31,689 Rabeprazole users. Check the latest studies of Rabeprazole.

What is Hepsera?

Hepsera has active ingredients of adefovir dipivoxil. It is often used in hepatitis b. eHealthMe is studying from 3,113 Hepsera users. Check the latest studies of Hepsera.

On Jul, 26, 2026

21 people who take Rabeprazole and Hepsera together, and have interactions are studied.

Rabeprazole and Hepsera drug interactions.

What are the common drug interactions of Rabeprazole and Hepsera, by gender? *:

female:

Blood parathyroid hormone increased
Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium)
Renal disorder (kidney disease)
Acidosis (build-up of carbon dioxide in the blood)
Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Asthenia (weakness)
Back pain
Blood alkaline phosphatase increased
Blood creatine increased
Blood creatinine increased

male:

Ascites (accumulation of fluid in the abdominal cavity)
Decreased appetite
Aminoaciduria (presence of amino acids in the urine)
Arthralgia (joint pain)
Electrolyte imbalance
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Femoral neck fracture (neck of femur bone fracture)
Hyperphosphatasaemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood)
Hypophosphataemia (electrolyte disturbance in which there is an abnormally low level of phosphate in the blood)
Hypouricaemia (level of uric acid in the blood that is abnormally high)

What are the common drug interactions of Rabeprazole and Hepsera, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Alanine aminotransferase increased
Asthenia (weakness)
Blood creatinine increased
Blood phosphorus decreased
Blood uric acid decreased
Bone density decreased
Glucose urine present
Hyperplasia (enlargement of an organ or tissue)
Intervertebral disc degeneration (spinal disc degeneration)
Intervertebral disc protrusion (spinal disc protrusion)

60+:

Ascites (accumulation of fluid in the abdominal cavity)
Decreased appetite
Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium)
Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
Renal disorder (kidney disease)
Aminoaciduria (presence of amino acids in the urine)
Arthralgia (joint pain)
Electrolyte imbalance
Fanconi syndrome acquired (self developed genetic disease of kidney damage due to defective transport system)
Femoral neck fracture (neck of femur bone fracture)

What are the existing conditions these people have? *

Pulmonary Mycosis (lung infection caused by yeast-like fungi): 4 people, 19.05%
Pain: 4 people, 19.05%
Mucormycosis (a rare infection caused by organisms that belong to a group of fungi called mucoromycotina): 4 people, 19.05%
Hepatic Neoplasm Malignant (liver cancer): 4 people, 19.05%
Hepatic Cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue): 4 people, 19.05%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 9.52%
Ascites (accumulation of fluid in the abdominal cavity): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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