Rabeprazole and Naltrexone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rabeprazole (rabeprazole sodium) and Naltrexone (naltrexone). Common drug interactions include rheumatoid arthritis among females and electrolyte imbalance among males.

The phase IV clinical study analyzes what interactions people have when they take Rabeprazole and Naltrexone. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Rabeprazole?

Rabeprazole has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 31,689 Rabeprazole users. Check the latest studies of Rabeprazole.

What is Naltrexone?

Naltrexone has active ingredients of naltrexone. eHealthMe is studying from 4,835 Naltrexone users. Check the latest studies of Naltrexone.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 17, 2026

27 people who take Rabeprazole and Naltrexone together, and have interactions are studied.

Rabeprazole and Naltrexone drug interactions.

What are the common drug interactions of Rabeprazole and Naltrexone, by gender? *:

female:

Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Abdominal pain
Abdominal pain upper
Balance disorder
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Body temperature fluctuation
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cestode infection (infection of the digestive tract by adult parasitic flatworms called cestodes or tapeworms)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Constipation

male:

Electrolyte imbalance
Type 2 diabetes mellitus

What are the common drug interactions of Rabeprazole and Naltrexone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Agitation (state of anxiety or nervous excitement)
Anxiety
Confusional state
Depression
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dysphemia (stammering or stuttering)
Hallucination (an experience involving the perception of something not present)
Hostility
Insomnia (sleeplessness)
Irritability

40-49:

Abdominal pain
Abdominal pain upper
Balance disorder
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Body temperature fluctuation
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cestode infection (infection of the digestive tract by adult parasitic flatworms called cestodes or tapeworms)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Constipation
Decreased appetite

50-59:

Cough
Lower respiratory tract infection

60+:

Electrolyte imbalance
Type 2 diabetes mellitus

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 21 people, 77.78%
Nasopharyngitis (inflammation of the nasopharynx): 17 people, 62.96%
Nausea (feeling of having an urge to vomit): 16 people, 59.26%
Headache (pain in head): 15 people, 55.56%
Colitis (inflammation of colon): 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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