Rabeprazole and Vicodin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rabeprazole (rabeprazole sodium) and Vicodin (acetaminophen; hydrocodone bitartrate). Common drug interactions include discomfort among females and dizziness among males.

The phase IV clinical study analyzes what interactions people have when they take Rabeprazole and Vicodin. It is created by eHealthMe based on reports of 69 people who take the same drugs from the FDA, and is updated regularly.

What is Rabeprazole?

Rabeprazole has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 31,689 Rabeprazole users. Check the latest studies of Rabeprazole.

What is Vicodin?

Vicodin has active ingredients of acetaminophen; hydrocodone bitartrate. It is often used in pain. eHealthMe is studying from 63,357 Vicodin users. Check the latest studies of Vicodin.

On Jul, 08, 2026

69 people who take Rabeprazole and Vicodin together, and have interactions are studied.

Rabeprazole and Vicodin drug interactions.

What are the common drug interactions of Rabeprazole and Vicodin, by gender? *:

female:

Discomfort
Eating disorder
Emotional distress
Gingivitis (inflammation of gums)
Injury
Neuropathy peripheral (surface nerve damage)
Osteomyelitis (infection of bone)
Pain in jaw
Parotitis (inflammation of a parotid gland)
Periodontal disease (disease that attacks the gum and bone and around the teeth)

male:

Dizziness
Fall
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Chest pain
Chronic kidney disease
Contusion (a type of hematoma of tissue in which capillaries)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Dyspnoea (difficult or laboured respiration)
Epistaxis (bleed from the nose)
Eructation (release of gas from the digestive tract)

What are the common drug interactions of Rabeprazole and Vicodin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)
Anxiety
Chest wall pain
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Eye rolling
Injection site burning
Muscle twitching
Nervousness

40-49:

Swelling face
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Asthenia (weakness)
Deformity (disfigurement)
Dental caries
Discomfort
Eating disorder
Emotional distress
Gingivitis (inflammation of gums)

50-59:

Disease recurrence
Headache (pain in head)
Hyperlipidaemia (presence of excess lipids in the blood)
Hypertension (high blood pressure)
Spinal osteoarthritis (joint cartilage loss in spine)
Weight increased
Abdominal distension
Abdominal hernia
Abortion spontaneous (naturally occurring miscarriage)
Alanine aminotransferase increased

60+:

Blood urea increased
Exostosis (formation of new bone on the surface of a bone)
Anxiety
Blood creatinine increased
Fatigue (feeling of tiredness)
Hypertension (high blood pressure)
Injury
Malaise (a feeling of general discomfort or uneasiness)
Oedema peripheral (superficial swelling)
Pain in extremity

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 17 people, 24.64%
Multiple Myeloma (cancer of the plasma cells): 11 people, 15.94%
Insomnia (sleeplessness): 6 people, 8.70%
High Blood Pressure: 5 people, 7.25%
Stress And Anxiety: 4 people, 5.80%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 4 people, 5.80%

* Approximation only. Some reports may have incomplete information.

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