Lansoprazole and Xtampza er drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lansoprazole (lansoprazole) and Xtampza er (oxycodone). Common drug interactions include asthenia among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Lansoprazole and Xtampza er. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Lansoprazole?

Lansoprazole has active ingredients of lansoprazole. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 129,663 Lansoprazole users. Check the latest studies of Lansoprazole.

What is Xtampza er?

Xtampza er has active ingredients of oxycodone. eHealthMe is studying from 1,502 Xtampza er users. Check the latest studies of Xtampza er.



On Jul, 08, 2026

12 people who take Lansoprazole and Xtampza er together, and have interactions are studied.

Lansoprazole and Xtampza er drug interactions.

What are the common drug interactions of Lansoprazole and Xtampza Er, by gender? *:

female:

  1. Asthenia (weakness)
  2. Constipation
  3. Ear infection
  4. Ear pain
  5. Erythema (redness of the skin)
  6. Facial pain
  7. Headache (pain in head)
  8. Migraine (headache)
  9. Nausea (feeling of having an urge to vomit)
  10. Pain

male:

  1. Death
  2. Malignant neoplasm of thorax (cancer tumour of rib cage)
  3. Pain in extremity
  4. Sepsis (a severe blood infection that can lead to organ failure and death)
  5. Anxiety
  6. Arthralgia (joint pain)
  7. Asthenia (weakness)
  8. Decreased appetite
  9. Fatigue (feeling of tiredness)
  10. Infection

What are the common drug interactions of Lansoprazole and Xtampza Er, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Ear pain
  2. Erythema (redness of the skin)
  3. Facial pain
  4. Fatigue (feeling of tiredness)
  5. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
  6. Headache (pain in head)
  7. Migraine (headache)
  8. Nausea (feeling of having an urge to vomit)
  9. Pain
  10. Pain in extremity

60+:

  1. Hypercapnia (too much smoke)
  2. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  3. Respiratory depression (respiration has a rate below 12 breaths)
  4. Respiratory failure (inadequate gas exchange by the respiratory system)
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Pericardial effusion (fluid around the heart)

What are the existing conditions these people have? *

  1. Pain: 5 people, 41.67%
  2. Stress And Anxiety: 4 people, 33.33%
  3. Skin Irritation: 4 people, 33.33%
  4. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 4 people, 33.33%
  5. Nausea (feeling of having an urge to vomit): 4 people, 33.33%
  6. Muscle Spasms (muscle contraction): 4 people, 33.33%
  7. Constipation: 4 people, 33.33%
  8. Chest Pain: 4 people, 33.33%
  9. Nausea And Vomiting: 3 people, 25.00%
  10. Immunodeficiency Common Variable: 3 people, 25.00%

* Approximation only. Some reports may have incomplete information.

Do you take Lansoprazole and Xtampza er?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Lansoprazole and Xtampza er:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Lansoprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Xtampza er:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lansoprazole and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Xtampza er and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on lansoprazole and oxycodone (the active ingredients of Lansoprazole and Xtampza er, respectively), and Lansoprazole and Xtampza er (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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