Ramelteon and Hydroxyurea drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ramelteon (ramelteon) and Hydroxyurea (hydroxyurea). Common drug interactions include death among females and dehydration among males.

The phase IV clinical study analyzes what interactions people have when they take Ramelteon and Hydroxyurea. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Ramelteon?

Ramelteon has active ingredients of ramelteon. It is often used in insomnia. eHealthMe is studying from 1,387 Ramelteon users. Check the latest studies of Ramelteon.

What is Hydroxyurea?

Hydroxyurea has active ingredients of hydroxyurea. It is often used in polycythemia vera. eHealthMe is studying from 17,240 Hydroxyurea users. Check the latest studies of Hydroxyurea.



On Aug, 08, 2026

13 people who take Ramelteon and Hydroxyurea together, and have interactions are studied.

Ramelteon and Hydroxyurea drug interactions.

What are the common drug interactions of Ramelteon and Hydroxyurea, by gender? *:

female:

  1. Death
  2. Diarrhoea
  3. Dysphonia (speech disorder attributable to a disorder of phonation)
  4. Failure to thrive (inadequate weight gain and physical growth in children)
  5. Ocular icterus (presence of jaundice seen in the sclera of the eye)
  6. Pericarditis (inflammation of the pericardium)
  7. Peripheral swelling
  8. Rosacea (a skin condition that causes facial redness)
  9. White blood cell disorder
  10. Fungal sepsis (whole body infection by fungus)

male:

  1. Dehydration (dryness resulting from the removal of water)
  2. Diarrhoea
  3. Fatigue (feeling of tiredness)
  4. Syncope (loss of consciousness with an inability to maintain postural tone)
  5. Febrile neutropenia (fever with reduced white blood cells)
  6. Mucosal inflammation (infection of mucous membrane)
  7. Odynophagia (painful swallowing, in the mouth (oropharynx) or oesophagus)
  8. Rash

What are the common drug interactions of Ramelteon and Hydroxyurea, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Mucosal inflammation (infection of mucous membrane)
  3. Odynophagia (painful swallowing, in the mouth (oropharynx) or oesophagus)
  4. Rash

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Fungal sepsis (whole body infection by fungus)
  2. Diarrhoea
  3. Pericarditis (inflammation of the pericardium)
  4. Peripheral swelling
  5. Rosacea (a skin condition that causes facial redness)
  6. White blood cell disorder
  7. Dehydration (dryness resulting from the removal of water)
  8. Fatigue (feeling of tiredness)
  9. Syncope (loss of consciousness with an inability to maintain postural tone)
  10. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)

What are the existing conditions these people have? *

  1. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 9 people, 69.23%
  2. High Blood Pressure: 6 people, 46.15%
  3. Neuropathy Peripheral (surface nerve damage): 5 people, 38.46%
  4. Adverse Event: 5 people, 38.46%
  5. Back Pain: 5 people, 38.46%
  6. Constipation: 5 people, 38.46%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 38.46%
  8. Hyperlipidaemia (presence of excess lipids in the blood): 5 people, 38.46%
  9. White Blood Cell Count Increased: 5 people, 38.46%
  10. Type 2 Diabetes: 5 people, 38.46%

* Approximation only. Some reports may have incomplete information.

Do you take Ramelteon and Hydroxyurea?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ramelteon and Hydroxyurea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ramelteon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Hydroxyurea:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ramelteon and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Hydroxyurea and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ramelteon and hydroxyurea (the active ingredients of Ramelteon and Hydroxyurea, respectively), and Ramelteon and Hydroxyurea (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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