Enablex and Zithromax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Enablex (darifenacin hydrobromide) and Zithromax (azithromycin). Common drug interactions include arthralgia among females and arthralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Enablex and Zithromax. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Enablex?

Enablex has active ingredients of darifenacin hydrobromide. It is often used in urge incontinence. eHealthMe is studying from 4,934 Enablex users. Check the latest studies of Enablex.

What is Zithromax?

Zithromax has active ingredients of azithromycin. It is often used in sinusitis. eHealthMe is studying from 35,525 Zithromax users. Check the latest studies of Zithromax.



On Aug, 08, 2026

34 people who take Enablex and Zithromax together, and have interactions are studied.

Enablex and Zithromax drug interactions.

What are the common drug interactions of Enablex and Zithromax, by gender? *:

female:

  1. Arthralgia (joint pain)
  2. Dizziness
  3. Pain in extremity
  4. Spinal osteoarthritis (joint cartilage loss in spine)
  5. Bone disorder
  6. Cardiac failure congestive
  7. Groin pain
  8. Injury
  9. Joint effusion (presence of extra fluid in joint covering)
  10. Osteonecrosis of jaw (death of bone of jaw)

male:

  1. Arthralgia (joint pain)
  2. Depression
  3. Anxiety
  4. Apraxia (disorder that affects a person's ability to organize the movements of the muscles used in speech)
  5. Arrhythmia (irregular heartbeat)
  6. Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)
  7. Arteriosclerosis (thickening and hardening of arteries)
  8. Asthenia (weakness)
  9. Ataxia (loss of full control of bodily movements)
  10. Back pain

What are the common drug interactions of Enablex and Zithromax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Abasia (inability to walk)
  2. Cellulitis (infection under the skin)
  3. Gastric haemorrhage (bleeding stomach)
  4. Hepatic failure (liver failure)
  5. Neuropathy peripheral (surface nerve damage)
  6. Pain
  7. Pelvic haemorrhage (pelvic bleeding)
  8. Pelvic mass
  9. Stomach mass
  10. Thrombosis (formation of a blood clot inside a blood vessel)

40-49:

  1. Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
  2. Pneumonia
  3. Anxiety
  4. Arachnoiditis (neuropathic disease caused by inflammation of the arachnoid)
  5. Arthralgia (joint pain)
  6. Back pain
  7. Cervicobrachial syndrome (pain in neck and arm with changing location)
  8. Chronic kidney disease
  9. Constipation
  10. Dystonia (abnormal muscle tone)

50-59:

  1. Breast cancer recurrent
  2. Cardiac failure congestive
  3. Cellulitis (infection under the skin)
  4. Chest wall mass
  5. Chondromalacia (anterior knee pain due to irritation of the cartilage on the under surface of the kneecap)
  6. Decreased appetite
  7. Deformity (disfigurement)
  8. Diarrhoea
  9. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
  10. Dizziness

60+:

  1. Arthralgia (joint pain)
  2. Dizziness
  3. Cardiac failure congestive
  4. Dysphonia (speech disorder attributable to a disorder of phonation)
  5. Groin pain
  6. Injury
  7. Joint effusion (presence of extra fluid in joint covering)
  8. Neurofibroma (non-cancerous tumours that grow on nerves throughout the body)
  9. Osteonecrosis of jaw (death of bone of jaw)
  10. Pain in extremity

What are the existing conditions these people have? *

  1. Breast Cancer: 8 people, 23.53%
  2. Pain: 7 people, 20.59%
  3. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 6 people, 17.65%
  4. Muscle Spasms (muscle contraction): 5 people, 14.71%
  5. Metastases To Bone (cancer spreads to bone): 4 people, 11.76%
  6. Osteoporosis (bones weak and more likely to break): 4 people, 11.76%
  7. Multiple Myeloma (cancer of the plasma cells): 4 people, 11.76%
  8. Depression: 3 people, 8.82%
  9. High Blood Cholesterol: 2 people, 5.88%
  10. Bladder Spasm: 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Enablex and Zithromax?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Enablex and Zithromax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Enablex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zithromax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Enablex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zithromax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on darifenacin hydrobromide and azithromycin (the active ingredients of Enablex and Zithromax, respectively), and Enablex and Zithromax (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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