Ramipril and Saphris drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Ramipril (ramipril) and Saphris (asenapine maleate). Common drug interactions include amnesia among females and depression among males.
The phase IV clinical study analyzes what interactions people have when they take Ramipril and Saphris. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.
What is Ramipril?
Ramipril has active ingredients of ramipril. It is often used in high blood pressure. eHealthMe is studying from 147,397 Ramipril users. Check the latest studies of Ramipril.
What is Saphris?
Saphris has active ingredients of asenapine maleate. It is often used in bipolar i disorder. eHealthMe is studying from 8,688 Saphris users. Check the latest studies of Saphris.
27 people who take Ramipril and Saphris together, and have interactions are studied.

What are the common drug interactions of Ramipril and Saphris, by gender? *:
female:
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Anxiety
- Arthralgia (joint pain)
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Arthropathy
- Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
- Dyspnoea (difficult or laboured respiration)
- Ear infection
- Pneumonia
- Pulmonary thrombosis (scarring in the lungs)
male:
- Depression
- Hallucination, auditory (perceiving sounds without auditory stimulus)
- Psychiatric symptom
- Insomnia (sleeplessness)
- Dyskinesia (abnormality or impairment of voluntary movement)
- Dysstasia (difficulty in standing)
- Gait disturbance
- Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
- Muscle spasms (muscle contraction)
- Muscle strain (an injury to a muscle in which the muscle fibres tear)
What are the common drug interactions of Ramipril and Saphris, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Hallucination, visual (seeing things that aren't there)
- Hypoglycaemia (deficiency of glucose in the bloodstream)
- Psychotic disorder
- Suicidal ideation
- Psychiatric symptom
- Insomnia (sleeplessness)
- Dyskinesia (abnormality or impairment of voluntary movement)
- Dysstasia (difficulty in standing)
- Gait disturbance
60+:
- Cholecystitis (infection of gallbladder)
- Drug intolerance (drug sensitivity)
- Blood glucose increased
- Dizziness
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Thirst
- Vomiting
What are the existing conditions these people have? *
- Stress And Anxiety: 19 people, 70.37%
- Insomnia (sleeplessness): 19 people, 70.37%
- Affective Disorder (mental disorder): 19 people, 70.37%
- Depression: 17 people, 62.96%
- Sleep Disorder: 16 people, 59.26%
- Diabetes: 16 people, 59.26%
- Heart Attack: 14 people, 51.85%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 14 people, 51.85%
- Chest Pain: 14 people, 51.85%
- Reflux Gastritis (a condition in which the lining of a person's stomach becomes inflamed as a result of exposure to bile): 5 people, 18.52%
* Approximation only. Some reports may have incomplete information.
Do you take Ramipril and Saphris?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Ramipril and Saphris:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Ramipril:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Saphris:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ramipril and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Saphris and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on ramipril and asenapine maleate (the active ingredients of Ramipril and Saphris, respectively), and Ramipril and Saphris (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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