Ranitidine and Acthar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ranitidine (ranitidine) and Acthar (corticotropin). Common drug interactions include asthenia among females and irritability among males.

The phase IV clinical study analyzes what interactions people have when they take Ranitidine and Acthar. It is created by eHealthMe based on reports of 42 people who take the same drugs from the FDA, and is updated regularly.

What is Ranitidine?

Ranitidine has active ingredients of ranitidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 234,475 Ranitidine users. Check the latest studies of Ranitidine.

What is Acthar?

Acthar has active ingredients of corticotropin. eHealthMe is studying from 4,948 Acthar users. Check the latest studies of Acthar.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

42 people who take Ranitidine and Acthar together, and have interactions are studied.

Ranitidine and Acthar drug interactions.

What are the common drug interactions of Ranitidine and Acthar, by gender? *:

female:

Asthenia (weakness)
Bradycardia (abnormally slow heart action)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Diarrhoea
Drug effect decreased
Dyspnoea (difficult or laboured respiration)
Hallucination (an experience involving the perception of something not present)
Hospitalisation
Intervertebral disc disorder (spinal disc disorder)
Mood altered (changes in mood)

male:

Irritability
Muscle spasms (muscle contraction)
Local swelling (swelling at the site of some application of substance or injury)
Pneumonia
Swelling face
Delirium (wild excitement)
Hypersomnia (excessive daytime sleepiness (eds))
Incoherent (talking in a confused and unclear way)
Nausea (feeling of having an urge to vomit)
Pain

What are the common drug interactions of Ranitidine and Acthar, by age (0-1 to 60+)? *:

0-1:

Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Hyperphagia (an abnormal appetite for food)
Insomnia (sleeplessness)
Irritability
Drug administration error
Pneumonia
Bradycardia (abnormally slow heart action)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Mood altered (changes in mood)
Neutropenia (an abnormally low number of neutrophils)

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Disturbance in attention
Drug ineffective
Pneumonia
Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
Epistaxis (bleed from the nose)
Headache (pain in head)
Muscular weakness (muscle weakness)
Neck mass (mass in neck)
Rash erythematous (redness of the skin)

40-49:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Drug effect decreased
Gait disturbance
Hospitalisation
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Pain
Rehabilitation therapy

50-59:

Fall
Fracture
Injection site haemorrhage (bleeding from injection site)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Ocular discomfort (a generic expression when there is lack of ease in/about the eyes)
Fatigue (feeling of tiredness)
Anxiety
Depression
Muscular weakness (muscle weakness)
Neuropathy peripheral (surface nerve damage)

60+:

General physical health deterioration (weak health status)
Skin ulcer
Stomatitis (inflammation of mucous membrane of mouth)

What are the existing conditions these people have? *

Infantile Spasms: 9 people, 21.43%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 6 people, 14.29%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 7.14%
Nephrotic Syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema): 3 people, 7.14%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 7.14%
Gait Disturbance: 3 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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