Promacta and Systemic lupus erythematosus - a phase IV clinical study of FDA data

Summary:

Systemic lupus erythematosus is reported as a side effect among people who take Promacta (eltrombopag olamine), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Cellcept, and have Idiopathic thrombocytopenic purpura.

The phase IV clinical study analyzes which people have Systemic lupus erythematosus when taking Promacta. It is created by eHealthMe based on reports of 17,717 people who have side effects when taking Promacta from the FDA, and is updated regularly.

What is Promacta?

Promacta has active ingredients of eltrombopag olamine. It is often used in idiopathic thrombocytopenic purpura (itp). eHealthMe is studying from 17,758 Promacta users. Check the latest studies of Promacta.

What is Systemic lupus erythematosus?

Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue) is found to be associated with 1,087 drugs and 1,645 conditions by eHealthMe. Check the latest studies of Systemic lupus erythematosus.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

17,717 people reported to have side effects when taking Promacta.
Among them, 20 people (0.11%) have Systemic lupus erythematosus.

Could Promacta cause Systemic lupus erythematosus?

Among these 20 people:

How long have people been on Promacta when they have Systemic lupus erythematosus? *

What is the gender of people who have Systemic lupus erythematosus when taking Promacta? *

female: 85 %
male: 15 %

What is the age of people who have Systemic lupus erythematosus when taking Promacta? *

What are other drugs people take besides Promacta? *

What are other side effects people have besides Systemic lupus erythematosus? *

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 2 people, 10.00%
Platelet Disorder: 2 people, 10.00%
Haemoglobin Abnormal: 2 people, 10.00%
Thrombosis (formation of a blood clot inside a blood vessel): 2 people, 10.00%
Drug Ineffective: 2 people, 10.00%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 2 people, 10.00%
Thrombocytopenia (decrease of platelets in blood): 2 people, 10.00%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 1 person, 5.00%
Adrenal Insufficiency (a condition in which the adrenal glands do not produce adequate amounts of steroids): 1 person, 5.00%
Bedridden: 1 person, 5.00%

What are the existing conditions these people have? *

Idiopathic Thrombocytopenic Purpura (bleeding disorder in which the immune system destroys platelets, which are necessary for normal blood clotting): 6 people, 30.00%
Thrombocytopenia (decrease of platelets in blood): 2 people, 10.00%
Autoimmune Thrombocytopenia (isolated low platelet count (thrombocytopenia) with normal bone marrow and the absence of other causes of thrombocytopenia): 2 people, 10.00%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 1 person, 5.00%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 1 person, 5.00%
Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Promacta and have Systemic lupus erythematosus?

- Check whether Systemic lupus erythematosus is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Promacta:

Promacta (17,758 reports)

Browse all side effects of Promacta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Systemic lupus erythematosus:

Systemic lupus erythematosus (1,087 drugs)

Browse all the conditions that are associated with Systemic lupus erythematosus:

Systemic lupus erythematosus (1,645 conditions)

Related publications that referenced our studies

Hania A, "Pyoderma Gangrenosum in a Patient With Systemic Lupus Erythematosus: Case Report", Journal of Medical Cases, 2014 Aug .
Hu P, Lu L, Hu B, Deng F, Fei WJ, "Cyclophosphamide‐Induced Hypertensive Encephalopathy in a Young Girl With Lupus", The Journal of Clinical Hypertension, 2012 Apr .
Hania A, "Pyoderma Gangrenosum in a Patient With Systemic Lupus Erythematosus: Case Report", Journal of Medical Cases, 2014 Aug .
Hu P, Lu L, Hu B, Deng F, Fei WJ, "Cyclophosphamide‐Induced Hypertensive Encephalopathy in a Young Girl With Lupus", The Journal of Clinical Hypertension, 2012 Apr .

How the study uses the data?

The study uses data from the FDA. It is based on eltrombopag olamine (the active ingredients of Promacta) and Promacta (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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