Rapaflo and Diclofenac drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rapaflo (silodosin) and Diclofenac (diclofenac). Common drug interactions include atypical pneumonia among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Rapaflo and Diclofenac. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Rapaflo?

Rapaflo has active ingredients of silodosin. It is often used in prostate examination abnormal. eHealthMe is studying from 3,929 Rapaflo users. Check the latest studies of Rapaflo.

What is Diclofenac?

Diclofenac has active ingredients of diclofenac. eHealthMe is studying from 41,319 Diclofenac users. Check the latest studies of Diclofenac.



On Jul, 16, 2026

22 people who take Rapaflo and Diclofenac together, and have interactions are studied.

Rapaflo and Diclofenac drug interactions.

What are the common drug interactions of Rapaflo and Diclofenac, by gender? *:

female:

  1. Atypical pneumonia (acute respiratory disease marked by high fever and coughing)
  2. Blindness
  3. Contusion (a type of hematoma of tissue in which capillaries)
  4. Disability
  5. Fall

male:

  1. Pyrexia (fever)
  2. Pain
  3. Prostatic disorder
  4. Rhinorrhoea (watery mucus discharge from the nose)
  5. Type 2 diabetes mellitus
  6. Blood pressure increased
  7. Obstruction
  8. Orchitis (inflammation of the testes)
  9. Blood glucose decreased
  10. Blood pressure decreased

What are the common drug interactions of Rapaflo and Diclofenac, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
  2. Nephrolithiasis (calculi in the kidneys)

50-59:

  1. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  2. Foot fracture

60+:

  1. Nausea (feeling of having an urge to vomit)
  2. Pain
  3. Prostatic disorder
  4. Rhinorrhoea (watery mucus discharge from the nose)
  5. Type 2 diabetes mellitus
  6. Blood pressure increased
  7. Obstruction
  8. Orchitis (inflammation of the testes)
  9. Blood glucose decreased
  10. Blood pressure decreased

What are the existing conditions these people have? *

  1. Primary Immunodeficiency Syndrome: 6 people, 27.27%
  2. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 18.18%
  3. Urinary Tract Infection: 3 people, 13.64%
  4. Immunodeficiency Common Variable: 3 people, 13.64%
  5. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 9.09%
  6. Pain: 2 people, 9.09%
  7. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Rapaflo and Diclofenac?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Rapaflo and Diclofenac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Rapaflo:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Diclofenac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Rapaflo and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Diclofenac and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on silodosin and diclofenac (the active ingredients of Rapaflo and Diclofenac, respectively), and Rapaflo and Diclofenac (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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