Xiidra and Stroke - a phase IV clinical study of FDA data

Summary:

Stroke is reported as a side effect among people who take Xiidra (lifitegrast), especially for people who are female, 60+ old, also take Synthroid, and have Dry eyes.

The phase IV clinical study analyzes which people have Stroke when taking Xiidra. It is created by eHealthMe based on reports of 15,181 people who have side effects when taking Xiidra from the FDA, and is updated regularly.

What is Xiidra?

Xiidra has active ingredients of lifitegrast. eHealthMe is studying from 15,244 Xiidra users. Check the latest studies of Xiidra.

What is Stroke?

Stroke (sudden death of a portion of the brain cells due to a lack of oxygen) is found to be associated with 2,309 drugs and 3,030 conditions by eHealthMe. Check the latest studies of Stroke.

On Jul, 16, 2026

15,181 people reported to have side effects when taking Xiidra.
Among them, 49 people (0.32%) have Stroke.

Among these 49 people:

What is the gender of people who have Stroke when taking Xiidra? *

female: 75.51 %
male: 24.49 %

What is the age of people who have Stroke when taking Xiidra? *

What are other drugs people take besides Xiidra? *

What are other side effects people have besides Stroke? *

Dry Eyes (lack of adequate tears): 8 people, 16.33%
Hypoaesthesia (reduced sense of touch or sensation): 7 people, 14.29%
Vision Blurred: 6 people, 12.24%
Heart Attack: 5 people, 10.20%
Memory Loss: 4 people, 8.16%
Feeling Abnormal: 4 people, 8.16%
Nervousness: 3 people, 6.12%
Eye Irritation: 3 people, 6.12%
Visual Impairment: 3 people, 6.12%
Taste - Impaired: 3 people, 6.12%

What are the existing conditions these people have? *

Dry Eyes (lack of adequate tears): 11 people, 22.45%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 4.08%
Thermal Burns Of Eye (burn of eye by heat): 1 person, 2.04%
Parkinson's Disease: 1 person, 2.04%
Hallucinations (sensations that appear real but are created by your mind): 1 person, 2.04%
Delusion (a false belief or opinion): 1 person, 2.04%
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection): 1 person, 2.04%
Asthma: 1 person, 2.04%

* Approximation only. Some reports may have incomplete information.

Do you take Xiidra and have Stroke?

- Check whether Stroke is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Xiidra:

Xiidra (15,244 reports)

Stroke treatments and more:

Stroke (334,635 reports)

Browse all side effects of Xiidra:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Stroke:

Stroke (2,309 drugs)

Browse all the conditions that are associated with Stroke:

Stroke (3,030 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on lifitegrast (the active ingredients of Xiidra) and Xiidra (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.