Rapaflo and Vitamin e drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rapaflo (silodosin) and Vitamin e (tocopherols and tocotrienols). Common drug interactions include back pain among females and dyspnoea among males.

The phase IV clinical study analyzes what interactions people have when they take Rapaflo and Vitamin e. It is created by eHealthMe based on reports of 27 people who take the same drugs from the FDA, and is updated regularly.

What is Rapaflo?

Rapaflo has active ingredients of silodosin. It is often used in prostate examination abnormal. eHealthMe is studying from 3,929 Rapaflo users. Check the latest studies of Rapaflo.

What is Vitamin e?

Vitamin e has active ingredients of tocopherols and tocotrienols. It is often used in vitamin supplementation. eHealthMe is studying from 42,279 Vitamin e users. Check the latest studies of Vitamin e.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 23, 2026

27 people who take Rapaflo and Vitamin e together, and have interactions are studied.

Rapaflo and Vitamin e drug interactions.

What are the common drug interactions of Rapaflo and Vitamin E, by gender? *:

female:

Back pain
Cervical vertebral fracture
Cystitis klebsiella (inflammation of the wall of the bladder by klebsiella)
Decreased appetite
Dizziness
Dysphagia (a condition in which swallowing is difficult or painful)
Fall
Hallucinations, mixed (sensations that appear real but are created by your mind -mixed)
Hospitalisation
Migraine (headache)

male:

Dyspnoea (difficult or laboured respiration)
Adverse drug reaction
Heart rate increased
Hypotension (abnormally low blood pressure)
Malaise (a feeling of general discomfort or uneasiness)
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Neoplasm malignant (cancer tumour)
Pain in extremity

What are the common drug interactions of Rapaflo and Vitamin E, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

50-59:

Migraine (headache)
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Tremor (trembling or shaking movements in one or more parts of your body)
Vomiting

60+:

Dyspnoea (difficult or laboured respiration)
Dizziness
Hypotension (abnormally low blood pressure)
Muscle strain (an injury to a muscle in which the muscle fibres tear)
Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Neoplasm malignant (cancer tumour)
Pain in extremity
Paranasal sinus discomfort
Rash pruritic (redness with itching)

What are the existing conditions these people have? *

High Blood Cholesterol: 4 people, 14.81%
Diabetes: 4 people, 14.81%
Sleep Disorder: 3 people, 11.11%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 3 people, 11.11%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 11.11%
Multiple Myeloma (cancer of the plasma cells): 3 people, 11.11%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 2 people, 7.41%
Neuropathy Peripheral (surface nerve damage): 2 people, 7.41%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 7.41%
Gait Disturbance: 2 people, 7.41%

* Approximation only. Some reports may have incomplete information.

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