Rapamune and Decadron drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Rapamune (sirolimus) and Decadron (dexamethasone). Common drug interactions include hyponatraemia among females and asthenia among males.
The phase IV clinical study analyzes what interactions people have when they take Rapamune and Decadron. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.
What is Rapamune?
Rapamune has active ingredients of sirolimus. It is often used in kidney transplant. eHealthMe is studying from 13,848 Rapamune users. Check the latest studies of Rapamune.
What is Decadron?
Decadron has active ingredients of dexamethasone. It is often used in multiple myeloma. eHealthMe is studying from 47,210 Decadron users. Check the latest studies of Decadron.
44 people who take Rapamune and Decadron together, and have interactions are studied.

What are the common drug interactions of Rapamune and Decadron, by gender? *:
female:
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Leukopenia (less number of white blood cells in blood)
- Vomiting
- Epistaxis (bleed from the nose)
- Mouth ulceration (mouth ulcers)
- Rash
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Anaemia (lack of blood)
- Disease progression
- Hypokalaemia (low potassium)
male:
- Asthenia (weakness)
- Dyspnoea (difficult or laboured respiration)
- Discomfort
- Dysphagia (a condition in which swallowing is difficult or painful)
- Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
- Headache (pain in head)
- Hyperhidrosis (abnormally increased sweating)
- Hypertension (high blood pressure)
- Incontinence (lack of moderation or self-control)
- Joint swelling
What are the common drug interactions of Rapamune and Decadron, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Asthenia (weakness)
- Blood pressure increased
- Cough
- Death
- Discomfort
- Dysphagia (a condition in which swallowing is difficult or painful)
- Dyspnoea (difficult or laboured respiration)
- Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
- Fatigue (feeling of tiredness)
- Headache (pain in head)
50-59:
- Dehydration (dryness resulting from the removal of water)
- Depressed level of consciousness
- Diarrhoea
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Lethargy (tiredness)
- Leukopenia (less number of white blood cells in blood)
- Mucosal inflammation (infection of mucous membrane)
- Pneumonia
- Activities of daily living impaired
- Aphagia (inability or refusal to swallow)
60+:
- Asthenia (weakness)
- Osteonecrosis (death of bone)
- Renal failure (kidney dysfunction)
- Atelectasis (partial or complete collapse of the lung)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Coma (state of unconsciousness lasting more than six hours)
- Drug intolerance (drug sensitivity)
- Drug toxicity
- Electrolyte imbalance
- Encephalitis (inflammation of the brain)
What are the existing conditions these people have? *
- Glioblastoma Multiforme (most common and deadliest of malignant primary brain tumours in adults): 23 people, 52.27%
* Approximation only. Some reports may have incomplete information.
Do you take Rapamune and Decadron?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Rapamune and Decadron:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Rapamune:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Decadron:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Rapamune and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Decadron and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Bartlett R, Hartle AJ, "Routine use of dexamethasone for postoperative nausea and vomiting: the case against", Anaesthesia, 2013 Sep .
- Bartlett R, Hartle AJ, "Routine use of dexamethasone for postoperative nausea and vomiting: the case against", Anaesthesia, 2013 Sep .
How the study uses the data?
The study uses data from the FDA. It is based on sirolimus and dexamethasone (the active ingredients of Rapamune and Decadron, respectively), and Rapamune and Decadron (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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