Rapamune and Levaquin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rapamune (sirolimus) and Levaquin (levofloxacin). Common drug interactions include haemoglobin decreased among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Rapamune and Levaquin. It is created by eHealthMe based on reports of 76 people who take the same drugs from the FDA, and is updated regularly.

What is Rapamune?

Rapamune has active ingredients of sirolimus. It is often used in kidney transplant. eHealthMe is studying from 13,848 Rapamune users. Check the latest studies of Rapamune.

What is Levaquin?

Levaquin has active ingredients of levofloxacin. It is often used in sinusitis. eHealthMe is studying from 56,638 Levaquin users. Check the latest studies of Levaquin.

On Jul, 13, 2026

76 people who take Rapamune and Levaquin together, and have interactions are studied.

Rapamune and Levaquin drug interactions.

What are the common drug interactions of Rapamune and Levaquin, by gender? *:

female:

Haemoglobin decreased
Nausea (feeling of having an urge to vomit)
Renal tubular necrosis (death of kidney tubules)
Vomiting
White blood cell count decreased
Epistaxis (bleed from the nose)
Haemorrhage (bleeding)
Mouth ulceration (mouth ulcers)
Rash
Somnolence (a state of near-sleep, a strong desire for sleep)

male:

Fatigue (feeling of tiredness)
Asthenia (weakness)
General physical health deterioration (weak health status)
Hyperlipidaemia (presence of excess lipids in the blood)
Hypokalaemia (low potassium)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Osteoporosis (bones weak and more likely to break)
Upper respiratory tract infection
Malaise (a feeling of general discomfort or uneasiness)
Vomiting

What are the common drug interactions of Rapamune and Levaquin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anxiety
Depression

20-29:

Thrombocytopenia (decrease of platelets in blood)
Post procedural complication
Respiratory failure (inadequate gas exchange by the respiratory system)
Abdominal infection
Abdominal pain upper
Acidosis (build-up of carbon dioxide in the blood)
Activated partial thromboplastin time prolonged
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Arterial occlusive disease (slow process through which arteries throughout the body become progressively narrowed and eventually completely blocked)

30-39:

Enzyme abnormality
Haemoglobin decreased
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Activated partial thromboplastin time prolonged
Alopecia (absence of hair from areas of the body)
Anoxia (low oxygen)
Apnoea (suspension of external breathing)
Asthenia (weakness)
Blood fibrinogen increased
Blood pressure diastolic decreased

40-49:

Cough
Dysphagia (a condition in which swallowing is difficult or painful)
Vomiting
Asthenia (weakness)
Blood pressure increased
Death
Discomfort
Dyspnoea (difficult or laboured respiration)
Ecchymosis (a discoloration of the skin resulting from bleeding underneath)
Fatigue (feeling of tiredness)

50-59:

Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Haematuria (presence of blood in urine)
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Osteoporosis (bones weak and more likely to break)
Tremor (trembling or shaking movements in one or more parts of your body)
Upper respiratory tract infection
Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection)
Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
Anaemia (lack of blood)
Anxiety

60+:

Blood urea increased
Blood creatinine increased
Bladder cancer
Blood alkaline phosphatase increased
Blood glucose increased
Blood lactate dehydrogenase increased
Haematocrit decreased
Haemoglobin decreased
Nasopharyngitis (inflammation of the nasopharynx)
Rash pruritic (redness with itching)

What are the existing conditions these people have? *

High Blood Pressure: 7 people, 9.21%
Pain: 6 people, 7.89%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 7.89%
High Blood Cholesterol: 4 people, 5.26%

* Approximation only. Some reports may have incomplete information.

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