Rebif and Dynacirc drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Rebif (interferon beta-1a) and Dynacirc (isradipine). Common drug interactions include hepatic enzyme increased among females and asthma among males.
The phase IV clinical study analyzes what interactions people have when they take Rebif and Dynacirc. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Rebif?
Rebif has active ingredients of interferon beta-1a. It is often used in multiple sclerosis. eHealthMe is studying from 61,126 Rebif users. Check the latest studies of Rebif.
What is Dynacirc?
Dynacirc has active ingredients of isradipine. eHealthMe is studying from 975 Dynacirc users. Check the latest studies of Dynacirc.
12 people who take Rebif and Dynacirc together, and have interactions are studied.

What are the common drug interactions of Rebif and Dynacirc, by gender? *:
female:
- Hepatic enzyme increased
- Breast cancer in situ
- Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Foot deformity (functional disability of foot)
- Gastrointestinal infection (infection of stomach and intestine)
- Hepatic steatosis (fatty liver disease)
- Localised infection (infection at the single location)
- Osteomyelitis (infection of bone)
- Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
male:
- Asthma
- Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
- Nasopharyngitis (inflammation of the nasopharynx)
- Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
- Nervousness
- Pain
- Pain in jaw
- Skin hypertrophy (skin cells enlarges)
- Skin induration (an abnormally hard spot or area on the skin)
- Umbilical hernia (an outward bulging (protrusion) of the abdominal lining or part of the abdominal organ(s) through the area around the belly button)
What are the common drug interactions of Rebif and Dynacirc, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Asthma
- Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
- Depression
- Extremity contracture (permanent shortening of a muscle or joint of arms and legs)
- Fatigue (feeling of tiredness)
- Hallucination (an experience involving the perception of something not present)
- Joint contracture (a permanent shortening of a muscle or joint)
- Joint stiffness
- Memory impairment
- Mobility decreased (ability to move is reduced)
40-49:
n/a
50-59:
- Ulcer
- Abasia (inability to walk)
- Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis)
- Blood disorder
- Breast cancer
- Glycosylated haemoglobin increased
- Headache (pain in head)
- Hepatic pain (pain in liver)
- Loss of consciousness
- Post procedural infection
60+:
- Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
- Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
What are the existing conditions these people have? *
- High Blood Pressure: 2 people, 16.67%
* Approximation only. Some reports may have incomplete information.
Do you take Rebif and Dynacirc?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Rebif and Dynacirc:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Rebif:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Dynacirc:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Rebif and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Dynacirc and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on interferon beta-1a and isradipine (the active ingredients of Rebif and Dynacirc, respectively), and Rebif and Dynacirc (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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