Reclast and Seroquel drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Reclast (zoledronic acid) and Seroquel (quetiapine fumarate). Common drug interactions include loss of consciousness among females and arthralgia among males.
The phase IV clinical study analyzes what interactions people have when they take Reclast and Seroquel. It is created by eHealthMe based on reports of 71 people who take the same drugs from the FDA, and is updated regularly.
What is Reclast?
Reclast has active ingredients of zoledronic acid. It is often used in osteoporosis. eHealthMe is studying from 15,774 Reclast users. Check the latest studies of Reclast.
What is Seroquel?
Seroquel has active ingredients of quetiapine fumarate. It is often used in bipolar disorder. eHealthMe is studying from 120,285 Seroquel users. Check the latest studies of Seroquel.
71 people who take Reclast and Seroquel together, and have interactions are studied.

What are the common drug interactions of Reclast and Seroquel, by gender? *:
female:
- Loss of consciousness
- Mass
- Staphylococcal infection (an infection with staphylococcus bacteria)
- Chills (felling of cold)
- Confusional state
- Urinary tract infection
- Blood pressure increased
- Cough
- Death
- Headache (pain in head)
male:
- Arthralgia (joint pain)
- Ankylosing spondylitis (type of arthritis affecting the spine)
- Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
- Cataract (clouding of the lens inside the eye)
- Dysphagia (a condition in which swallowing is difficult or painful)
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Glaucoma (increased fluid pressure in the eye with vision loss)
- Immune system disorder
- Injection site bruising
What are the common drug interactions of Reclast and Seroquel, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Cystitis (inflammation of the wall of the bladder)
- Ileus (a painful obstruction of the ileum or other part of the intestine)
- Influenza
- Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
- Nasopharyngitis (inflammation of the nasopharynx)
- Urinary tract infection
- Viral infection
- Arthralgia (joint pain)
- Bone disorder
- Dysstasia (difficulty in standing)
40-49:
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Pyrexia (fever)
- Analgesic drug level increased
- Blood alkaline phosphatase increased
- Blood urea increased
- Blood urea nitrogen/creatinine ratio increased
- Bone pain
- Chest pain
- Decreased appetite
50-59:
- Mass
- Myalgia (muscle pain)
- Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
- Staphylococcal infection (an infection with staphylococcus bacteria)
- Back pain
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Migraine (headache)
- Pneumonia
- Ankylosing spondylitis (type of arthritis affecting the spine)
- Aortic aneurysm (enlargement of an aortic artery caused by a weakening of the artery wall)
60+:
- Dyspnoea (difficult or laboured respiration)
- Pain
- Confusional state
- Crying
- Disease recurrence
- Dry mouth
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Gait disturbance
- Malaise (a feeling of general discomfort or uneasiness)
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
What are the existing conditions these people have? *
- Stress And Anxiety: 12 people, 16.90%
- Depression: 9 people, 12.68%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 9.86%
- Migraine (headache): 7 people, 9.86%
- High Blood Cholesterol: 7 people, 9.86%
- Sleep Disorder: 6 people, 8.45%
- Pain: 6 people, 8.45%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 7.04%
- Insomnia (sleeplessness): 5 people, 7.04%
- Indigestion: 4 people, 5.63%
* Approximation only. Some reports may have incomplete information.
Do you take Reclast and Seroquel?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Reclast and Seroquel:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Reclast:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Seroquel:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Reclast and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Seroquel and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Mati?, K., & Pele?, A. M. , "Drug-induced toxic hepatitis associated with the combination of quetiapine and fluphenazine: A case report", The European Journal of Psychiatry, 2018 Jan .
- Shah Z, Londhe V, "Influence of various media on the dissolution profiles of immediate-release quetiapine tablets in India", Dissolution Technologies, 2016 Feb .
- Mati?, K., & Pele?, A. M. , "Drug-induced toxic hepatitis associated with the combination of quetiapine and fluphenazine: A case report", The European Journal of Psychiatry, 2018 Jan .
- Shah Z, Londhe V, "Influence of various media on the dissolution profiles of immediate-release quetiapine tablets in India", Dissolution Technologies, 2016 Feb .
How the study uses the data?
The study uses data from the FDA. It is based on zoledronic acid and quetiapine fumarate (the active ingredients of Reclast and Seroquel, respectively), and Reclast and Seroquel (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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