Reglan and Ocrevus drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Reglan (metoclopramide hydrochloride) and Ocrevus (ocrelizumab). Common drug interactions include fall among females.
The phase IV clinical study analyzes what interactions people have when they take Reglan and Ocrevus. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.
What is Reglan?
Reglan has active ingredients of metoclopramide hydrochloride. It is often used in gastroparesis. eHealthMe is studying from 29,455 Reglan users. Check the latest studies of Reglan.
What is Ocrevus?
Ocrevus has active ingredients of ocrelizumab. eHealthMe is studying from 56,583 Ocrevus users. Check the latest studies of Ocrevus.
28 people who take Reglan and Ocrevus together, and have interactions are studied.

What are the common drug interactions of Reglan and Ocrevus, by gender? *:
female:
- Fall
- Muscle spasms (muscle contraction)
- Rash
- Optic neuritis (optic nerve inflammation)
- Vasculitis (inflammation of a blood vessel or blood vessels)
- Asthenia (weakness)
- Influenza
- Abdominal pain
- Cardiac valve disease (heart valve disease)
- Chills (felling of cold)
male:
n/a
What are the common drug interactions of Reglan and Ocrevus, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Anaemia (lack of blood)
- Arthralgia (joint pain)
- Cerebral artery occlusion (blockage of blood vessel of brain by fat or clot)
- Cerebral artery stenosis (hardening of brain blood vessels)
- Cerebral infarction (less blood supply to brain resulting tissue damage)
- Chest pain
- Chronic kidney disease
- Depression
- Dilated cardiomyopathy
30-39:
- Urinary tract infection
- Back pain
- Ephelides (tanned macules found on the skin)
- Fungal infection
- Melanocytic naevus (a type of lesion that contains nevus cells (a type of melanocyte))
- Herpes zoster
- Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
40-49:
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Hypopituitarism (diminished hormone secretion by the pituitary gland, causing dwarfism in children and premature aging in adults)
- Impaired healing
- Infection
- Loss of proprioception (loss of senses of body and parts)
- Memory impairment
- Myalgia (muscle pain)
- Pyrexia (fever)
- Sinusitis (inflammation of sinus)
- Vasculitis (inflammation of a blood vessel or blood vessels)
50-59:
- Optic neuritis (optic nerve inflammation)
- Fall
- Angle closure glaucoma (term used for several ocular diseases that ultimately result in increased intraocular pressure (iop) and decreased visual acuity)
- Asthma
- Blood cholesterol increased
- Foot fracture
- Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
- Impaired gastric emptying
- Infusion related reaction
- Pityriasis rosea (itchy rash develops over the trunk and extremities)
60+:
- Asthenia (weakness)
- Muscle spasms (muscle contraction)
- Epigastric discomfort
- Gastritis (inflammation of stomach)
- Heart rate increased
- Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
- Hypertension (high blood pressure)
- Malaise (a feeling of general discomfort or uneasiness)
- Oral herpes (viral infection of mouth)
- Oropharyngeal pain
What are the existing conditions these people have? *
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 11 people, 39.29%
- Pain: 11 people, 39.29%
- Nausea (feeling of having an urge to vomit): 9 people, 32.14%
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 25.00%
- Muscle Spasms (muscle contraction): 7 people, 25.00%
- Migraine (headache): 6 people, 21.43%
- Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 6 people, 21.43%
- Neurogenic Bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion): 4 people, 14.29%
- Arrhythmias (irregular heartbeat): 4 people, 14.29%
- Clonus (series of involuntary, rhythmic, muscular contractions and relaxations): 4 people, 14.29%
* Approximation only. Some reports may have incomplete information.
Do you take Reglan and Ocrevus?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Reglan and Ocrevus:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Reglan:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ocrevus:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Reglan and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ocrevus and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on metoclopramide hydrochloride and ocrelizumab (the active ingredients of Reglan and Ocrevus, respectively), and Reglan and Ocrevus (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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