Reglan and Stadol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Reglan (metoclopramide hydrochloride) and Stadol (butorphanol tartrate). Common drug interactions include emotional distress among females and hospitalisation among males.

The phase IV clinical study analyzes what interactions people have when they take Reglan and Stadol. It is created by eHealthMe based on reports of 88 people who take the same drugs from the FDA, and is updated regularly.

What is Reglan?

Reglan has active ingredients of metoclopramide hydrochloride. It is often used in gastroparesis. eHealthMe is studying from 29,455 Reglan users. Check the latest studies of Reglan.

What is Stadol?

Stadol has active ingredients of butorphanol tartrate. It is often used in migraine. eHealthMe is studying from 5,546 Stadol users. Check the latest studies of Stadol.

On Jul, 13, 2026

88 people who take Reglan and Stadol together, and have interactions are studied.

What are the common drug interactions of Reglan and Stadol, by gender? *:

female:

Emotional distress
Enteritis (inflammation of the small intestine)
Epistaxis (bleed from the nose)
Faecal incontinence (a lack of control over passing stool)
Fall
Flushing (the warm, red condition of human skin)
Gallbladder disorder
Gastritis (inflammation of stomach)
Haemoglobin decreased
Heart rate increased

male:

Hospitalisation
Anxiety
Cardiac disorder
Chordee (a condition in which the head of the penis curves downward or upward, at the junction of the head)
Deformity (disfigurement)
Dependence
Depression
Developmental delay
Dizziness
Drug addiction

What are the common drug interactions of Reglan and Stadol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Chordee (a condition in which the head of the penis curves downward or upward, at the junction of the head)
Deformity (disfigurement)
Developmental delay
Drug withdrawal syndrome neonatal (prenatal nas is caused by discontinuation of drugs taken by the pregnant mother)
Emotional distress
Encephalopathy (functioning of the brain is affected by some agent or condition)
Eustachian tube dysfunction (eustachian tube problems like clearing the ears when flying, suffering infection, and recurring ear infection)
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Muscular weakness (muscle weakness)
Otitis media acute (rapid inflammation of the middle ear)

10-19:

n/a

20-29:

Menorrhagia (an abnormally heavy bleeding and prolonged menstrual period at regular intervals)
Abdominal pain
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Cholecystitis chronic (long lasting infection of gallbladder)
Drug ineffective
Emotional disorder
Emotional distress
General physical health deterioration (weak health status)

30-39:

Cellulitis (infection under the skin)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dependence
Depression
Dizziness
Drug addiction
Dysgeusia (disorder of the sense of taste)
Dyspnoea (difficult or laboured respiration)
Embolism arterial (blood clot that has travelled through your arteries and become stuck)

40-49:

Anxiety
Abdominal pain
Back pain
Overdose
Suicide attempt
Abdominal pain upper
Chest pain
Hypotension (abnormally low blood pressure)
Respiratory failure (inadequate gas exchange by the respiratory system)
Impaired gastric emptying

50-59:

Drug hypersensitivity
Dysphagia (a condition in which swallowing is difficult or painful)
Epiglottic oedema (swelling and inflammation of the epiglottis)
Failure to thrive (inadequate weight gain and physical growth in children)
Feeding disorder (when children refuse to eat certain food groups)
Hallucination (an experience involving the perception of something not present)
Premature baby
Pulmonary artery atresia (lungs artery absent)
Pulmonary artery stenosis congenital (congenital -narrowing (stenosis) that occurs in the lung artery)
Speech disorder

60+:

Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Labyrinthitis (inflammation of the labyrinth or inner ear)
Seborrhoeic keratosis (noncancerous (benign) skin growths that some people develop as they age. they often appear on the back or chest)
Drug hypersensitivity
Drug ineffective
Hallucination (an experience involving the perception of something not present)
Retinal haemorrhage (bleeding from retina)
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)

What are the existing conditions these people have? *

Pain: 27 people, 30.68%
Nausea (feeling of having an urge to vomit): 26 people, 29.55%
Constipation: 23 people, 26.14%
High Blood Pressure: 22 people, 25.00%
Stress And Anxiety: 22 people, 25.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 20 people, 22.73%
Bipolar Disorder (mood disorder): 19 people, 21.59%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 18 people, 20.45%
Fever: 18 people, 20.45%
Abdominal Pain: 18 people, 20.45%

* Approximation only. Some reports may have incomplete information.

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