Asacol and Isoniazid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Asacol (mesalamine) and Isoniazid (isoniazid). Common drug interactions include arthralgia among females and bronchitis among males.

The phase IV clinical study analyzes what interactions people have when they take Asacol and Isoniazid. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Asacol?

Asacol has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 20,618 Asacol users. Check the latest studies of Asacol.

What is Isoniazid?

Isoniazid has active ingredients of isoniazid. It is often used in tuberculosis. eHealthMe is studying from 20,174 Isoniazid users. Check the latest studies of Isoniazid.

On Jul, 13, 2026

29 people who take Asacol and Isoniazid together, and have interactions are studied.

What are the common drug interactions of Asacol and Isoniazid, by gender? *:

female:

Arthralgia (joint pain)
Myalgia (muscle pain)
Abdominal pain
Back pain
Mycobacterium tuberculosis complex test positive
Neck pain
Alopecia (absence of hair from areas of the body)
Antinuclear factor positive
Blood creatinine increased
Creatinine renal clearance decreased

male:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Death
Eosinophilia (eosinophil count in the peripheral blood exceeds)
Haematuria (presence of blood in urine)
Injection site erythema (redness at injection site)
Kidney small
Leukocyturia (presence of white blood cells in urine)
Lower limb fracture
Lymphocyte percentage decreased

What are the common drug interactions of Asacol and Isoniazid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Alopecia (absence of hair from areas of the body)

20-29:

Diarrhoea
Dysgeusia (disorder of the sense of taste)
Hepatic necrosis (large portions of liver die off due to severe liver disease)
Hepatitis acute
Hepatotoxicity (chemical-driven liver damage)
Injection site pain

30-39:

Peritoneal tuberculosis

40-49:

Generalised oedema (swelling all over the body)
Haemorrhage subcutaneous (bleeding from skin)
Arthralgia (joint pain)
Renal tubular atrophy (wasting of kidney tubules)
Urinary casts
Antinuclear factor positive
Blood creatinine increased
Blood immunoglobulin g increased
Blood immunoglobulin m increased
Creatinine renal clearance decreased

50-59:

Arthralgia (joint pain)
Back pain
Myalgia (muscle pain)
Mycobacterium tuberculosis complex test positive
Neck pain
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Pneumocystis jiroveci pneumonia (fungal infection of the lungs)
Anaemia (lack of blood)
Abdominal pain

60+:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Pneumonia
Death
Lower limb fracture
Mycobacterium tuberculosis complex test positive
Palpitations (feelings or sensations that your heart is pounding or racing)

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 3 people, 10.34%
Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 10.34%
High Blood Pressure: 3 people, 10.34%
Depression: 3 people, 10.34%
Constipation: 3 people, 10.34%
Bowel Movement Irregularity: 3 people, 10.34%
Mycobacterium Tuberculosis Complex Test Positive: 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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