Melatonin and Erleada drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Melatonin (melatonin) and Erleada (apalutamide). Common drug interactions include fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Melatonin and Erleada. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Melatonin?

Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 56,212 Melatonin users. Check the latest studies of Melatonin.

What is Erleada?

Erleada has active ingredients of apalutamide. eHealthMe is studying from 7,519 Erleada users. Check the latest studies of Erleada.

On Jul, 13, 2026

20 people who take Melatonin and Erleada together, and have interactions are studied.

Melatonin and Erleada drug interactions.

What are the common drug interactions of Melatonin and Erleada, by gender? *:

female:

n/a

male:

Fatigue (feeling of tiredness)
Breast enlargement
Fall
Hallucination (an experience involving the perception of something not present)
Hot flush (sudden feelings of heat)
Muscle spasms (muscle contraction)
Pancreatitis (inflammation of pancreas)
Prostatic specific antigen increased
Asthenia (weakness)
Back pain

What are the common drug interactions of Melatonin and Erleada, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Cheyne-stokes respiration (abnormal pattern of breathing combination of slow and faster)
Encephalopathy (functioning of the brain is affected by some agent or condition)
Hepatic failure (liver failure)
Hypovolaemia (a decreased volume of circulating blood in the body)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Sepsis (a severe blood infection that can lead to organ failure and death)
Urosepsis (secondary infection that occurs when a urinary tract infection spreads to the bloodstream)

60+:

Breast enlargement
Fatigue (feeling of tiredness)
Muscle spasms (muscle contraction)
Prostatic specific antigen increased
Asthenia (weakness)
Back pain
Blood glucose increased
Dyspnoea (difficult or laboured respiration)
Feeling cold
Gait disturbance

What are the existing conditions these people have? *

Prostate Cancer: 11 people, 55.00%
Sleep Disorder: 4 people, 20.00%
Restless Leg Syndrome (a powerful urge to move your legs): 4 people, 20.00%
Renal Cell Carcinoma (a kidney cancer): 4 people, 20.00%
Pain: 4 people, 20.00%
Sinus Disorder (disease of sinus): 2 people, 10.00%
Prostate Cancer Metastatic: 2 people, 10.00%
Paranasal Sinus Hypersecretion: 2 people, 10.00%
Immune System Disorder: 2 people, 10.00%
High Blood Pressure: 2 people, 10.00%

* Approximation only. Some reports may have incomplete information.

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